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OriGene in recent publications
Repurposing of Proton Pump Inhibitors as first identified small molecule inhibitors of endo-β-N-acetylglucosaminidase (ENGase) for the treatment of NGLY1 deficiency, a rare genetic disease Bioorg. Med. Chem. Lett. 2017 [ENGASE]

Glucose-regulated protein 78 autoantibody associates with blood-brain barrier disruption in neuromyelitis optica Sci Transl Med 2017 [HSPA5]

Amplification of F-Actin Disassembly and Cellular Repulsion by Growth Factor Signaling Dev. Cell 2017 [STK38L]

Tyr42 phosphorylation of RhoA GTPase promotes tumorigenesis through nuclear factor (NF)-κB Free Radic. Biol. Med. 2017 [VAV2]

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32 Lysate belong to pathway "maturity onset diabetes of the young"


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LY400059NM_000162GCKTransient overexpression lysate of glucokinase (hexokinase 4) (GCK), transcript variant 1 5 days
LY400074NM_000209PDX1Transient overexpression lysate of pancreatic and duodenal homeobox 1 (PDX1) In Stock
LY400078NM_000207INSTransient overexpression lysate of insulin (INS) In Stock
LY400107NM_000280PAX6Transient overexpression lysate of paired box 6 (PAX6), transcript variant 1 In Stock
LY400113NM_000298PKLRTransient overexpression lysate of pyruvate kinase, liver and RBC (PKLR), nuclear gene encoding mitochondrial protein, transcript variant 1 5 days
LY400146NM_000415IAPPTransient overexpression lysate of islet amyloid polypeptide (IAPP) In Stock
LY400161NM_000457HNF4ATransient overexpression lysate of hepatocyte nuclear factor 4, alpha (HNF4A), transcript variant 2 In Stock
LY400162NM_000458HNF1BTransient overexpression lysate of HNF1 homeobox B (HNF1B), transcript variant 1 5 days
LY400185NM_000545HNF1ATransient overexpression lysate of HNF1 homeobox A (HNF1A) In Stock
LY400891NM_002500NEUROD1Transient overexpression lysate of neurogenic differentiation 1 (NEUROD1) In Stock
LY401255NM_003822NR5A2Transient overexpression lysate of nuclear receptor subfamily 5, group A, member 2 (NR5A2), transcript variant 2 5 days
LY401428NM_004497FOXA3Transient overexpression lysate of forkhead box A3 (FOXA3) 5 days
LY401429NM_004498ONECUT1Transient overexpression lysate of one cut homeobox 1 (ONECUT1) 5 days
LY401692NM_005515MNX1Transient overexpression lysate of motor neuron and pancreas homeobox 1 (MNX1), transcript variant 1 5 days
LY401859NM_006168NKX6Transient overexpression lysate of NK6 homeobox 1 (NKX6-1) 5 days
LY402827NM_020999NEUROG3Transient overexpression lysate of neurogenin 3 (NEUROG3) 5 days
LY403250NM_033508GCKTransient overexpression lysate of glucokinase (hexokinase 4) (GCK), transcript variant 3 5 days
LY404473NM_201589MAFATransient overexpression lysate of v-maf musculoaponeurotic fibrosarcoma oncogene homolog A (avian) (MAFA) 5 days
LY405861NM_178850HNF4ATransient overexpression lysate of hepatocyte nuclear factor 4, alpha (HNF4A), transcript variant 3 5 days
LY406171NM_177455BHLHA15Transient overexpression lysate of basic helix-loop-helix family, member a15 (BHLHA15) 5 days


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