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OriGene in recent publications
Repurposing of Proton Pump Inhibitors as first identified small molecule inhibitors of endo-β-N-acetylglucosaminidase (ENGase) for the treatment of NGLY1 deficiency, a rare genetic disease Bioorg. Med. Chem. Lett. 2017 [ENGASE]

The lipid moiety 7-ketocholesteryl-9-carboxynonanoate mediates binding interaction of oxLDL to LOX-1 and upregulates ABCA1 expression through PPARγ Life Sci. 2017 [OLR1]

Human GRP78 affinity towards its signaling partners Ire1α and PERK is differently modulated by an unfolded protein client Biochem. Biophys. Res. Commun. 2017 [HSPA5]

Human GRP78 affinity towards its signaling partners Ire1α and PERK is differently modulated by an unfolded protein client Biochem. Biophys. Res. Commun. 2017 [ERN1]

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16 Lysate belong to pathway "steroid biosynthesis"

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SKUAccnSymbolDescriptionShipping
LY400269NM_000785CYP27B1Transient overexpression lysate of cytochrome P450, family 27, subfamily B, polypeptide 1 (CYP27B1), nuclear gene encoding mitochondrial protein In Stock
LY401419NM_004462FDFT1Transient overexpression lysate of farnesyl-diphosphate farnesyltransferase 1 (FDFT1) 5 days
LY401968NM_006579EBPTransient overexpression lysate of emopamil binding protein (sterol isomerase) (EBP) 5 days
LY402373NM_014762DHCR24Transient overexpression lysate of 24-dehydrocholesterol reductase (DHCR24) 5 days
LY413989NM_016371HSD17B7Transient overexpression lysate of hydroxysteroid (17-beta) dehydrogenase 7 (HSD17B7) 5 days
LY418574NM_003578SOAT2Transient overexpression lysate of sterol O-acyltransferase 2 (SOAT2) 5 days
LY418795NM_003273TM7SF2Transient overexpression lysate of transmembrane 7 superfamily member 2 (TM7SF2) 5 days
LY418884NM_003129SQLETransient overexpression lysate of squalene epoxidase (SQLE) 5 days
LY418898NM_003101SOAT1Transient overexpression lysate of sterol O-acyltransferase 1 (SOAT1), transcript variant 688113 5 days
LY419974NM_001360DHCR7Transient overexpression lysate of 7-dehydrocholesterol reductase (DHCR7), transcript variant 1 5 days
LY422643NM_001017369MSMO1Transient overexpression lysate of sterol-C4-methyl oxidase-like (SC4MOL), transcript variant 2 5 days
LY424356NM_001001438LSSTransient overexpression lysate of lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) (LSS), transcript variant 2 5 days
LY424848NM_000235LIPATransient overexpression lysate of lipase A, lysosomal acid, cholesterol esterase (LIPA), transcript variant 2 In Stock
LY426820NM_001127605LIPATransient overexpression lysate of lipase A, lysosomal acid, cholesterol esterase (LIPA), transcript variant 1 5 days
LY427043NM_001129765NSDHLTransient overexpression lysate of NAD(P) dependent steroid dehydrogenase-like (NSDHL), transcript variant 2 In Stock
LY431950NM_001163817DHCR7Transient overexpression lysate of 7-dehydrocholesterol reductase (DHCR7), transcript variant 2 5 days

 

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