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OriGene in recent publications
Repurposing of Proton Pump Inhibitors as first identified small molecule inhibitors of endo-β-N-acetylglucosaminidase (ENGase) for the treatment of NGLY1 deficiency, a rare genetic disease Bioorg. Med. Chem. Lett. 2017 [ENGASE]

Glucose-regulated protein 78 autoantibody associates with blood-brain barrier disruption in neuromyelitis optica Sci Transl Med 2017 [HSPA5]

Amplification of F-Actin Disassembly and Cellular Repulsion by Growth Factor Signaling Dev. Cell 2017 [STK38L]

Tyr42 phosphorylation of RhoA GTPase promotes tumorigenesis through nuclear factor (NF)-κB Free Radic. Biol. Med. 2017 [VAV2]

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144 TrueORF belong to pathway "complement and coagulation cascades"


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RC200499NM_001710CFBCFB (Myc-DDK-tagged)-Human complement factor B (CFB)Immediate
RC200736NM_203329CD59CD59 (Myc-DDK-tagged)-Human CD59 molecule, complement regulatory protein (CD59), transcript variant 33 week
RC201146NM_033011PLATPLAT (Myc-DDK-tagged)-Human plasminogen activator, tissue (PLAT), transcript variant 3Immediate
RC201222NM_002659PLAURPLAUR (Myc-DDK-tagged)-Human plasminogen activator, urokinase receptor (PLAUR), transcript variant 1Immediate
RC201615NM_000574CD55CD55 (Myc-DDK-tagged)-Human CD55 molecule, decay accelerating factor for complement (Cromer blood group) (CD55), transcript variant 1Immediate
RC202073NM_000313PROS1PROS1 (Myc-DDK-tagged)-Human protein S (alpha) (PROS1)Immediate
RC202082NM_000295SERPINA1SERPINA1 (Myc-DDK-tagged)-Human serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 (SERPINA1), transcript variant 1Immediate
RC202083NM_002658PLAUPLAU (Myc-DDK-tagged)-Human plasminogen activator, urokinase (PLAU), transcript variant 1Immediate
RC202085NM_000602SERPINE1SERPINE1 (Myc-DDK-tagged)-Human serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 (SERPINE1), transcript variant 1Immediate
RC202098NM_001032281TFPITFPI (Myc-DDK-tagged)-Human tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) (TFPI), transcript variant 2Immediate
RC202770NM_000509FGGFGG (Myc-DDK-tagged)-Human fibrinogen gamma chain (FGG), transcript variant gamma-AImmediate
RC202799NM_001017365C4BPBC4BPB (Myc-DDK-tagged)-Human complement component 4 binding protein, beta (C4BPB), transcript variant 3Immediate
RC202800NM_001872CPB2CPB2 (Myc-DDK-tagged)-Human carboxypeptidase B2 (plasma) (CPB2), transcript variant 1Immediate
RC203142NM_001993F3F3 (Myc-DDK-tagged)-Human coagulation factor III (thromboplastin, tissue factor) (F3), transcript variant 1Immediate
RC203599NM_000624SERPINA5SERPINA5 (Myc-DDK-tagged)-Human serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 (SERPINA5)Immediate
RC203767NM_000062SERPING1SERPING1 (Myc-DDK-tagged)-Human serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 (SERPING1), transcript variant 1Immediate
RC203784NM_001736C5AR1C5AR1 (Myc-DDK-tagged)-Human complement component 5a receptor 1 (C5AR1)Immediate
RC203821NM_000491C1QBC1QB (Myc-DDK-tagged)-Human complement component 1, q subcomponent, B chain (C1QB)Immediate
RC203832NM_172369C1QCC1QC (Myc-DDK-tagged)-Human complement component 1, q subcomponent, C chain (C1QC), transcript variant 2Immediate
RC204436NM_000710BDKRB1BDKRB1 (Myc-DDK-tagged)-Human bradykinin receptor B1 (BDKRB1)Immediate


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