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OriGene in recent publications
Repurposing of Proton Pump Inhibitors as first identified small molecule inhibitors of endo-β-N-acetylglucosaminidase (ENGase) for the treatment of NGLY1 deficiency, a rare genetic disease Bioorg. Med. Chem. Lett. 2017 [ENGASE]

The lipid moiety 7-ketocholesteryl-9-carboxynonanoate mediates binding interaction of oxLDL to LOX-1 and upregulates ABCA1 expression through PPARγ Life Sci. 2017 [OLR1]

Human GRP78 affinity towards its signaling partners Ire1α and PERK is differently modulated by an unfolded protein client Biochem. Biophys. Res. Commun. 2017 [HSPA5]

Human GRP78 affinity towards its signaling partners Ire1α and PERK is differently modulated by an unfolded protein client Biochem. Biophys. Res. Commun. 2017 [ERN1]

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15445 TrueORF belong to family "druggable genome"

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SKUAccnSymbolDescriptionShipping
RC239809NM_001278669NFATC1NFATC1 (myc-DDK-tagged) - Human nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 (NFATC1), transcript variant 64 week
RC239823NM_001282470GRIK4GRIK4 (myc-DDK-tagged) - Human glutamate receptor, ionotropic, kainate 4 (GRIK4), transcript variant 14 week
RC239851NM_001301030GRIK5GRIK5 (myc-DDK-tagged) - Human glutamate receptor, ionotropic, kainate 5 (GRIK5), transcript variant 14 week
RC239930NM_001278616BUB1BUB1 (myc-DDK-tagged) - Human BUB1 mitotic checkpoint serine/threonine kinase (BUB1), transcript variant 24 week
RC239953NM_001286457USP7USP7 (myc-DDK-tagged) - Human ubiquitin specific peptidase 7 (herpes virus-associated) (USP7), transcript variant 24 week
RC239958NM_001281781ZMYND8ZMYND8 (myc-DDK-tagged) - Human zinc finger, MYND-type containing 8 (ZMYND8), transcript variant 154 week
RC240018NM_001286464BAIAP3BAIAP3 (myc-DDK-tagged) - Human BAI1-associated protein 3 (BAIAP3), transcript variant 65 week
RC240031NM_001289863PER3PER3 (myc-DDK-tagged) - Human period circadian clock 3 (PER3), transcript variant 35 week
RC240048NM_001281773ZMYND8ZMYND8 (myc-DDK-tagged) - Human zinc finger, MYND-type containing 8 (ZMYND8), transcript variant 75 week
RC240183NM_001301072MAP3K4MAP3K4 (myc-DDK-tagged) - Human mitogen-activated protein kinase kinase kinase 4 (MAP3K4), transcript variant 56 week
RC240190NM_001286583PHRF1PHRF1 (myc-DDK-tagged) - Human PHD and ring finger domains 1 (PHRF1), transcript variant 46 week
RC240191NM_001286582PHRF1PHRF1 (myc-DDK-tagged) - Human PHD and ring finger domains 1 (PHRF1), transcript variant 36 week
RC240216NM_001278074COL5A1COL5A1 (myc-DDK-tagged) - Human collagen, type V, alpha 1 (COL5A1), transcript variant 27 week
RC600003NM_201283EGFREGFR (DDK-His-tagged)-Extra Cellular Domain Clone of Homo sapiens epidermal growth factor receptor, transcript variant 3, Signal peptide (1-24) plus EC domain (25-405)Immediate
RC600056NM_005424TIE1TIE1 (DDK-His-tagged)-Extra Cellular Domain Clone of Homo sapiens tyrosine kinase with immunoglobulin-like and EGF-like domains 1, transcript variant 1, Signal peptide (1-21) plus EC domain (22-759)Immediate
RC224818NM_005021ENPP3ENPP3 (Myc-DDK-tagged)-Human ectonucleotide pyrophosphatase/phosphodiesterase 3 (ENPP3)Immediate
RC224930NM_001099293KIF4BKIF4B (Myc-DDK-tagged)-Human kinesin family member 4B (KIF4B)Immediate
RC224937NM_016184CLEC4ACLEC4A (Myc-DDK-tagged)-Human C-type lectin domain family 4, member A (CLEC4A), transcript variant 1Immediate
RC224975NM_005606LGMNLGMN (Myc-DDK-tagged)-Human legumain (LGMN), transcript variant 1Immediate
RC225088NM_001127670KCNE1KCNE1 (Myc-DDK-tagged)-Human potassium voltage-gated channel, Isk-related family, member 1 (KCNE1), transcript variant 1Immediate

 

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