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OriGene in recent publications
Repurposing of Proton Pump Inhibitors as first identified small molecule inhibitors of endo-β-N-acetylglucosaminidase (ENGase) for the treatment of NGLY1 deficiency, a rare genetic disease Bioorg. Med. Chem. Lett. 2017 [ENGASE]

Glucose-regulated protein 78 autoantibody associates with blood-brain barrier disruption in neuromyelitis optica Sci Transl Med 2017 [HSPA5]

Amplification of F-Actin Disassembly and Cellular Repulsion by Growth Factor Signaling Dev. Cell 2017 [STK38L]

Tyr42 phosphorylation of RhoA GTPase promotes tumorigenesis through nuclear factor (NF)-κB Free Radic. Biol. Med. 2017 [VAV2]

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15445 TrueORF belong to family "druggable genome"


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RC227429NM_001145014RFPL4ARFPL4A (Myc-DDK-tagged)-Human ret finger protein-like 4A (RFPL4A)Immediate
RC227431NM_001135604ESM1ESM1 (Myc-DDK-tagged)-Human endothelial cell-specific molecule 1 (ESM1), transcript variant 2Immediate
RC227438NM_001143836NOX4NOX4 (Myc-DDK-tagged)-Human NADPH oxidase 4 (NOX4), transcript variant 2Immediate
RC227444NM_001136258SGMS2SGMS2 (Myc-DDK-tagged)-Human sphingomyelin synthase 2 (SGMS2), transcript variant 3Immediate
RC227445NM_001144875DOK3DOK3 (Myc-DDK-tagged)-Human docking protein 3 (DOK3), transcript variant 23 week
RC227457NM_001135243TCOF1TCOF1 (Myc-DDK-tagged)-Human Treacher Collins-Franceschetti syndrome 1 (TCOF1), transcript variant 43 week
RC227458NM_001144909CLEC4MCLEC4M (Myc-DDK-tagged)-Human C-type lectin domain family 4, member M (CLEC4M), transcript variant 9. Note: ORF is codon optimized99 week
RC227463NM_001135863ETFBKMTMETTL20 (Myc-DDK-tagged)-Human methyltransferase like 20 (METTL20), transcript variant 2Immediate
RC227475NM_001142534SH2D3CSH2D3C (Myc-DDK-tagged)-Human SH2 domain containing 3C (SH2D3C), transcript variant 64 week
RC227476NM_001145102SMAD3SMAD3 (Myc-DDK-tagged)-Human SMAD family member 3 (SMAD3), transcript variant 23 week
RC227482NM_001145443PFKFB3PFKFB3 (Myc-DDK-tagged)-Human 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 (PFKFB3), transcript variant 2Immediate
RC227501NM_001135637PIP5K1APIP5K1A (Myc-DDK-tagged)-Human phosphatidylinositol-4-phosphate 5-kinase, type I, alpha (PIP5K1A), transcript variant 43 week
RC227540NM_001145357SIN3ASIN3A (Myc-DDK-tagged)-Human SIN3 homolog A, transcription regulator (yeast) (SIN3A), transcript variant 3Immediate
RC227555NM_001135244TCOF1TCOF1 (Myc-DDK-tagged)-Human Treacher Collins-Franceschetti syndrome 1 (TCOF1), transcript variant 599 week
RC227613NM_001142556HMMRHMMR (Myc-DDK-tagged)-Human hyaluronan-mediated motility receptor (RHAMM) (HMMR), transcript variant 13 week
RC227648NM_001142564CNGA1CNGA1 (Myc-DDK-tagged)-Human cyclic nucleotide gated channel alpha 1 (CNGA1), transcript variant 14 week
RC227678NM_001136478ANP32EANP32E (Myc-DDK-tagged)-Human acidic (leucine-rich) nuclear phosphoprotein 32 family, member E (ANP32E), transcript variant 299 week
RC227715NM_001135610PRDM2PRDM2 (Myc-DDK-tagged)-Human PR domain containing 2, with ZNF domain (PRDM2), transcript variant 4Immediate
RC227757NM_001143814BDNFBDNF (Myc-DDK-tagged)-Human brain-derived neurotrophic factor (BDNF), transcript variant 143 week
RC227777NM_001145143HTR3DHTR3D (Myc-DDK-tagged)-Human 5-hydroxytryptamine (serotonin) receptor 3 family member D (HTR3D), transcript variant 1Immediate


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