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OriGene in recent publications
Repurposing of Proton Pump Inhibitors as first identified small molecule inhibitors of endo-β-N-acetylglucosaminidase (ENGase) for the treatment of NGLY1 deficiency, a rare genetic disease Bioorg. Med. Chem. Lett. 2017 [ENGASE]

The lipid moiety 7-ketocholesteryl-9-carboxynonanoate mediates binding interaction of oxLDL to LOX-1 and upregulates ABCA1 expression through PPARγ Life Sci. 2017 [OLR1]

Human GRP78 affinity towards its signaling partners Ire1α and PERK is differently modulated by an unfolded protein client Biochem. Biophys. Res. Commun. 2017 [HSPA5]

Human GRP78 affinity towards its signaling partners Ire1α and PERK is differently modulated by an unfolded protein client Biochem. Biophys. Res. Commun. 2017 [ERN1]

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51 TrueClone belong to pathway "one carbon pool by folate"

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SKUAccnSymbolDescriptionShipping
SC105966BC008629MTHFD1LMTHFD1L (untagged)-Homo sapiens, DKFZP586G1517 protein, clone MGC:9660 IMAGE:3464498, complete cds0
SC111168NM_006636MTHFD2MTHFD2 (untagged)-ORIGENE UNIQUE VARIANT 1 of Human methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase (MTHFD2), nuclear gene encoding mitochondrial protein, transc4
SC111221NM_015440MTHFD1LMTHFD1L (untagged)-Human methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like (MTHFD1L), nuclear gene encoding mitochondrial protein0
SC111756NM_012190ALDH1L1ALDH1L1 (untagged)-Human aldehyde dehydrogenase 1 family, member L1 (ALDH1L1)0
SC116123NM_006441MTHFSMTHFS (untagged)-Human 5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase) (MTHFS), transcript variant 10
SC116397NM_005956MTHFD1MTHFD1 (untagged)-Human methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase (MTHFD1)0
SC119632NM_000819GARTGART (untagged)-Human phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase (GART), transcript variant 10
SC120689NM_139242MTFMTMTFMT (untagged)-Human mitochondrial methionyl-tRNA formyltransferase (MTFMT), nuclear gene encoding mitochondrial protein4
SC125742BC015062MTHFD2MTHFD2 (untagged)-Human methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase, mRNA (cDNA clone MGC:13506 IMAGE:4285669), complete cds3
SC125794BC032584SHMT2SHMT2 (untagged)-Human serine hydroxymethyltransferase 2 (mitochondrial), mRNA (cDNA clone MGC:45240 IMAGE:5499481), complete cds3
SC125935NM_005957MTHFRMTHFR (untagged)-Human methylenetetrahydrofolate reductase (NAD(P)H) (MTHFR)0
SC127313NM_148918SHMT1SHMT1 (untagged)-Human serine hydroxymethyltransferase 1 (soluble) (SHMT1), nuclear gene encoding mitochondrial protein, transcript variant 23
SC303805NM_006657FTCDFTCD (untagged)-Human formiminotransferase cyclodeaminase (FTCD), transcript variant B3
SC308351NM_206965FTCDFTCD (untagged)-Human formiminotransferase cyclodeaminase (FTCD), transcript variant A3
SC309934NM_000254MTRMTR (untagged)-Human 5-methyltetrahydrofolate-homocysteine methyltransferase (MTR)0
SC310521NM_006636MTHFD2MTHFD2 (untagged)-Human methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase (MTHFD2), nuclear gene encoding mitochondrial protein, transcript variant 13
SC311605AK091498SHMT1 (untagged)-Human cDNA FLJ34179 fis, clone FCBBF3016622, weakly similar to SERINE HYDROXYMETHYLTRANSFERASE, CYTOSOLIC (EC 2.1.2.1)3
SC312033AK055053SHMT2 (untagged)-Human cDNA FLJ30491 fis, clone BRAWH2000177, moderately similar to SERINE HYDROXYMETHYLTRANSFERASE, MITOCHONDRIAL PRECURSOR (EC 2.1.2.1)3
SC313318NM_000481AMTAMT (untagged)-Human aminomethyltransferase (AMT), nuclear gene encoding mitochondrial protein, transcript variant 10
SC313442NM_175085GARTGART (untagged)-Human phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase (GART), transcript variant 23

 

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