PLGF (PGF) (NM_002632) Human Recombinant Protein

CAT#: TP723864

Purified recombinant protein of Human placental growth factor (PGF / PLGF-1), transcript variant 1

Product Images

Specifications

Product Data

• Species: Human
• Expression Host: HEK293
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  Human PLGF, the region of Ala21-Arg149, from gene Accession# NM_002632
• Tag: Tag Free
• Predicted MW: 14.5 kDa
• Concentration: lot specific
• Purity: >95%, as determined by Coomassie stained SDS-PAGE.
• Buffer: 5 mM citric acid, 0.15 M NaCl, 5 mM NaHPO4, pH 4.0
• Bioactivity: The ED50 is 1-3 ng/ml, corresponding to a specific activity of 0.33 - 1 x 106 units/mg, determined by the dose dependent binding to VEGFR1-Fc chimera using a functional ELISA.
• Endotoxin: Less than 0.01 ng per µg protein as determined by the LAL method
• Storage: Store at -80°C.
• Stability: Unopened vial can be stored between 2°C and 8°C for up to 2 weeks, at -20°C for up to 6 months, or at -70°C or below until the expiration date. Aliquots can be stored between 2°C and 8°C for up to one week and stored at -20°C or colder for up to 3 months. Avoid repeated freeze/thaw cycles.

Reference Data

• RefSeq: NP_002623
• Locus ID: 5228
• UniProt ID: P49763, Q53XY6, Q86TW6
• Cytogenetics: 14q24.3
• Refseq Size: 1758
• Refseq ORF: 510
• Synonyms: D12S1900; PGFL; PIGF; PLGF; PlGF-2; SHGC-10760
• Summary: This gene encodes a growth factor found in placenta which is homologous to vascular endothelial growth factor. Alternatively spliced transcripts encoding different isoforms have been found for this gene.[provided by RefSeq, Jun 2011]
• Protein Families: Druggable Genome, Secreted Protein
• Protein Pathways: Bladder cancer, Focal adhesion, mTOR signaling pathway, Pancreatic cancer, Pathways in cancer, Renal cell carcinoma