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Home Recombinant Human Proteins All GADD45A Proteins

GADD45A (NM_001924) Purified Human Protein

Specifications Citations Customer Service Product Documents
Cat. No. Description Datasheet Price Availability*  
TP720561 Recombinant protein of human growth arrest and DNA-damage-inducible, alpha (GADD45A), 10 µg (Larger pack size?) 299 5 Days
TA150088 2B5, Anti-His mouse monoclonal antibody $248 In Stock
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OriGene Data
Species:Human Expression Host:E. coli
Expression cDNA Clone or AA Sequence
A DNA sequence from TrueORF clone, RC204005, encoding the full length polypeptide (Met1-Arg165) of human GADD45A
Tag:N-terminal HIS Predicted MW:20.5 kDa
Purity:>95% as determined by SDS-PAGE and Coomassie blue staining
Concentration:Resuspend the protein to the desired concentration in proper buffer.
Buffer:Lyophilized from a 0.2 µM filtered solution of 20mM Phosphate buffer, 150mM NaCl, pH 7.2. Stable for at least 6 months from date of receipt under proper storage and handling conditions.
Endotoxin: < 0.1 EU per µg protein as determined by LAL test
Protein Families: Stem cell - PluripotencyDruggable Genome
Protein Pathways: MAPK signaling pathwayCell cyclep53 signaling pathway
Protein Data
Protein Image
 

Reference Data
RefSeq: NP_001915 RefSeq Size: 1355 RefSeq ORF: 498
LocusID: 1647 Cytogenetic: 1p31.2  
Synonyms : DDIT1; GADD45
Summary: This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The protein encoded by this gene responds to environmental stresses by mediating activation of the p38/JNK pathway via MTK1/MEKK4 kinase. The DNA damage-induced transcription of this gene is mediated by both p53-dependent and -independent mechanisms. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.[provided by RefSeq, Dec 2010].
*: Inventory for certain proteins may be limited due to low expression level. Delivery time may vary from web posted schedule. Contact techsupport@origene.com for specific inventory information
**: DDK-tag is the same as FLAG tag. Flag® is a registered trademark of Sigma-Aldrich

 

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