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Home Recombinant Human Proteins All LAMTOR3 Proteins

LAMTOR3 (NM_021970) Purified Human Protein

Specifications Citations Customer Service Product Documents
Cat. No. Description Datasheet Price Availability*  
TP720523 Recombinant protein of human MAPK scaffold protein 1 (MAPKSP1), transcript variant 1, 10 µg (Larger pack size?) 299 5 Days
TA300464 Rabbit Monoclonal Antibody against MAP2K1IP1 (Clone Y130) $325 3-7 Days
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Also for LAMTOR3 (NM_021970)
cDNA Clone shRNA/siRNA Primer Pair Lysate Antibody

OriGene Data
Species:Human Expression Host:E. coli
Expression cDNA Clone or AA Sequence
A DNA sequence from TrueORF clone, RC204668, encoding the full length polypeptide (Met1-Val124) of human LAMTOR3
Tag:C-terminal HIS Predicted MW:15.8 kDa
Purity:>95% as determined by SDS-PAGE and Coomassie blue staining
Concentration:>50 ug/mL as determined by microplate BCA method
Buffer:20mM Tris-HCl, 100mM NaCl, 5mM DTT, 30% Glycerol, pH 8.0. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions.
Endotoxin: < 0.1 EU per µg protein as determined by LAL test
Protein Families: Druggable Genome
Protein Pathways: MAPK signaling pathway
Protein Data
Protein Image
 

Reference Data
RefSeq: NP_068805 RefSeq Size: 1416 RefSeq ORF: 375
LocusID: 8649 Cytogenetic: 4q23  
Synonyms : MAP2K1IP1; MAPBP; MAPKSP1; MP1; PRO0633; Ragulator3
Summary: This gene encodes a scaffold protein that functions in the extracellular signal-regulated kinase (ERK) cascade. The protein is localized to late endosomes by the mitogen-activated protein-binding protein-interacting protein, and binds specifically to MAP kinase kinase MAP2K1/MEK1, MAP kinase MAPK3/ERK1, and MAP kinase MAPK1/ERK2. Studies of the orthologous gene in mouse indicate that it regulates late endosomal traffic and cell proliferation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. A pseudogene of this gene is located on the long arm of chromosome 13. [provided by RefSeq, Aug 2011].
*: Inventory for certain proteins may be limited due to low expression level. Delivery time may vary from web posted schedule. Contact techsupport@origene.com for specific inventory information
**: DDK-tag is the same as FLAG tag. Flag® is a registered trademark of Sigma-Aldrich

 

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