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Home Recombinant Human Proteins All B4GALT4 Proteins

B4GALT4 (NM_003778) Purified Human Protein

Specifications Citations Customer Service Product Documents
Cat. No. Description Datasheet Price Availability*  
TP720426 Recombinant protein of human UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4 (B4GALT4), transcript variant 2, 10 µg (Larger pack size?) 299 5 Days
TA50011-100 4C5, Anti-DDK monoclonal antibody (100 μL) $248 In Stock
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OriGene Data
Species:Human Expression Host:HEK293 cells
Expression cDNA Clone or AA Sequence
A DNA sequence from TrueORF clone, RC209493, encoding the secreted form (Gln39-Ala344) of human B4GALT4
Tag:N-terminal GST and HIS Predicted MW:36.8 kDa
Purity:>95% as determined by SDS-PAGE and Coomassie blue staining
Concentration:>50 ug/mL as determined by microplate BCA method
Buffer:20mM Tris, 150mM NaCl, pH 7.5. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions.
Endotoxin: < 0.1 EU per µg protein as determined by LAL test
Protein Families: Transmembrane
Protein Pathways: Keratan sulfate biosynthesisGlycosphingolipid biosynthesis - lacto and neolacto seriesMetabolic pathways
Protein Data
Protein Image
 

Reference Data
RefSeq: NP_003769 RefSeq Size: 2283 RefSeq ORF: 1035
LocusID: 8702 Cytogenetic: 3q13.3  
Synonyms : B4Gal-T4; beta4Gal-T4
Summary: This gene is one of seven beta-1,4-galactosyltransferase (beta4GalT) genes. They encode type II membrane-bound glycoproteins that appear to have exclusive specificity for the donor substrate UDP-galactose; all transfer galactose in a beta1,4 linkage to similar acceptor sugars: GlcNAc, Glc, and Xyl. Each beta4GalT has a distinct function in the biosynthesis of different glycoconjugates and saccharide structures. As type II membrane proteins, they have an N-terminal hydrophobic signal sequence that directs the protein to the Golgi apparatus and which then remains uncleaved to function as a transmembrane anchor. By sequence similarity, the beta4GalTs form four groups: beta4GalT1 and beta4GalT2, beta4GalT3 and beta4GalT4, beta4GalT5 and beta4GalT6, and beta4GalT7. The enzyme encoded by this gene appears to mainly play a role in glycolipid biosynthesis. Two alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2008].
*: Inventory for certain proteins may be limited due to low expression level. Delivery time may vary from web posted schedule. Contact techsupport@origene.com for specific inventory information
**: DDK-tag is the same as FLAG tag. Flag® is a registered trademark of Sigma-Aldrich

 

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