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Home Recombinant Human Proteins All F11R Proteins

F11R (NM_016946) Purified Human Protein

Specifications Citations Customer Service Product Documents
Cat. No. Description Datasheet Price Availability*  
TP720393 Recombinant protein of human F11 receptor (F11R), 10 ug (Larger pack size?) $299 5 Days
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OriGene Data
Species:Human Expression Host:HEK293 cells
Expression cDNA Clone or AA Sequence
A DNA sequence from TrueORF clone, RC221478, encoding the secreted form (Ser28-Val238) of human JAM-A
Tag:Tag-free Predicted MW:23.9 kDa
Purity:>95% as determined by SDS-PAGE and Coomassie blue staining
Concentration:Resuspend the protein to the desired concentration in proper buffer.
Buffer:Lyophilized from a 0.2 µM filtered solution of 20mM Tris-HCl, 50mM NaCl, 100mM Glycine, pH 7.5. Stable for at least 6 months from date of receipt under proper storage and handling conditions.
Endotoxin: < 0.1 EU per µg protein as determined by LAL test
Protein Families: TransmembraneDruggable Genome
Protein Pathways: Cell adhesion molecules (CAMs)Tight junctionLeukocyte transendothelial migrationEpithelial cell signaling in Helicobacter pylori infection
Protein Data
Protein Image

Reference Data
RefSeq: NP_058642 RefSeq Size: 3660 RefSeq ORF: 900
LocusID: 50848 Cytogenetic: 1q21.2-q21.3  
Synonyms : CD321; JAM; JAM1; JAMA; JCAM; KAT; PAM-1
Summary: Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is an important regulator of tight junction assembly in epithelia. In addition, the encoded protein can act as (1) a receptor for reovirus, (2) a ligand for the integrin LFA1, involved in leukocyte transmigration, and (3) a platelet receptor. Multiple 5' alternatively spliced variants, encoding the same protein, have been identified but their biological validity has not been established. [provided by RefSeq, Jul 2008].
*: Inventory for certain proteins may be limited due to low expression level. Delivery time may vary from web posted schedule. Contact techsupport@origene.com for specific inventory information
**: DDK-tag is the same as FLAG tag. Flag® is a registered trademark of Sigma-Aldrich


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