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Home Recombinant Human Proteins All QPRT Proteins

QPRT (NM_014298) Purified Human Protein

Specifications Citations Customer Service Product Documents
Cat. No. Description Datasheet Price Availability*  
TP720230 Recombinant protein of human quinolinate phosphoribosyltransferase (QPRT), 10 ug (Larger pack size?) $399 5 Days
TA501519 anti-QPRT mouse monoclonal antibody, clone OTI4E5 (formerly 4E5) $325 In Stock
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OriGene Data
Species:Human Expression Host:E. coli
Expression cDNA Clone or AA Sequence
A DNA sequence from TrueORF clone, RC202960, encoding the full length polypeptide (Met1-His297) of human QPRT
Tag:C-terminal HIS Predicted MW:33 kDa
Purity:>95% as determined by SDS-PAGE and Coomassie blue staining
Concentration:>50 ug/mL as determined by microplate BCA method
Buffer:20mM Tris-HCl, 150mM NaCl, pH 8.0. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions.
Endotoxin: < 0.1 EU per µg protein as determined by LAL test
Protein Families:
Protein Pathways: Nicotinate and nicotinamide metabolismMetabolic pathways
Protein Data
Protein Image
 

Reference Data
RefSeq: NP_055113 RefSeq Size: 1575 RefSeq ORF: 894
LocusID: 23475 Cytogenetic: 16p11.2  
Synonyms : HEL-S-90n; QPRTase
Summary: This gene encodes a key enzyme in catabolism of quinolinate, an intermediate in the tryptophan-nicotinamide adenine dinucleotide pathway. Quinolinate acts as a most potent endogenous exitotoxin to neurons. Elevation of quinolinate levels in the brain has been linked to the pathogenesis of neurodegenerative disorders such as epilepsy, Alzheimer's disease, and Huntington's disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015].
*: Inventory for certain proteins may be limited due to low expression level. Delivery time may vary from web posted schedule. Contact techsupport@origene.com for specific inventory information
**: DDK-tag is the same as FLAG tag. Flag® is a registered trademark of Sigma-Aldrich

 

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