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Home Recombinant Human Proteins All LDHB Proteins

LDHB (NM_001174097) Purified Human Protein

Specifications Citations Customer Service Product Documents
Cat. No. Description Datasheet Price Availability*  
TP720210 Recombinant protein of human lactate dehydrogenase B (LDHB), transcript variant 2., 10 ug (Larger pack size?) $399 5 Days
TA300872 Rabbit Monoclonal Antibody against LDHB (Clone EP1566Y) $325 2 Weeks
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OriGene Data
Species:Human Expression Host:E. coli
Expression cDNA Clone or AA Sequence
A DNA sequence from TrueORF clone, RC229903, encoding the polypeptide (Ala2-Leu334) of human LDHB
Tag:C-terminal HIS Predicted MW:38.8 kDa
Purity:>95% as determined by SDS-PAGE and Coomassie blue staining
Concentration:>50 ug/mL as determined by microplate BCA method
Buffer:20mM Tris-HCl, 100mM NaCl, pH 8.0. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions.
Endotoxin: < 0.1 EU per µg protein as determined by LAL test
Protein Families: Druggable Genome
Protein Pathways: Glycolysis / GluconeogenesisCysteine and methionine metabolismPyruvate metabolismPropanoate metabolismMetabolic pathways
Protein Data
Protein Image
 

Reference Data
RefSeq: NP_001167568 RefSeq Size: RefSeq ORF: 1005
LocusID: 3945 Cytogenetic: 12p12.2-p12.1  
Synonyms : HEL-S-281; LDH-B; LDH-H; LDHBD; TRG-5
Summary: This gene encodes the B subunit of lactate dehydrogenase enzyme, which catalyzes the interconversion of pyruvate and lactate with concomitant interconversion of NADH and NAD+ in a post-glycolysis process. Alternatively spliced transcript variants have been found for this gene. Recent studies have shown that a C-terminally extended isoform is produced by use of an alternative in-frame translation termination codon via a stop codon readthrough mechanism, and that this isoform is localized in the peroxisomes. Mutations in this gene are associated with lactate dehydrogenase B deficiency. Pseudogenes have been identified on chromosomes X, 5 and 13. [provided by RefSeq, Feb 2016].
*: Inventory for certain proteins may be limited due to low expression level. Delivery time may vary from web posted schedule. Contact techsupport@origene.com for specific inventory information
**: DDK-tag is the same as FLAG tag. Flag® is a registered trademark of Sigma-Aldrich

 

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