OriGene Technologies, Inc.
Search:    
Left ProductsProducts divider ServicesServices divider technologyTechnology divider researchResearch divider TechsupportTechSupport divider AboutAbout Right
 
Home Recombinant Human Proteins All IL6 Proteins

IL6 (NM_000600) Purified Human Protein

Specifications Citations (0) Customer Service Product Documents
Cat. No. Description Datasheet Price Availability*  
TP720008 Recombinant protein of human interleukin 6 (interferon, beta 2) (IL6), the mature form (Pro29-Met212) with C-terminal His tag, 10 ug (Larger pack size?) $299 5 Days
TA300413 Rabbit Monoclonal Antibody against IL6 (Clone E457) $325 In Stock
Add to Shopping Cart
spacer
OriGene Data
Species:Human Expression Host:E. coli
Expression cDNA Clone or AA Sequence
A DNA sequence from TrueORF clone, RC202078, encoding the mature peptide (Pro29-Met212) of human IL6
Tag:C-terminal HIS Predicted MW:20.9 kDa
Purity:>95% as determined by SDS-PAGE and Coomassie blue staining
Concentration:Resuspend the protein to the desired concentration in proper buffer.
Buffer:Lyophilized from a 0.2 µM filtered solution of 20mM HAc-NaAc, 150mM NaCl, pH 5.0. Stable for at least 6 months from date of receipt under proper storage and handling conditions.
Endotoxin: < 0.1 EU per µg protein as determined by LAL test
BioActivity: ED50 is less than 0.1 ng/ml as determined by the dose-dependent stimulation of human TF-1 cells. Specific Activity of 5.0 x 107 IU/mg.
Protein Families: Secreted ProteinDruggable Genome
Protein Pathways: Cytokine-cytokine receptor interactionToll-like receptor signaling pathwayNOD-like receptor signaling pathwayCytosolic DNA-sensing pathwayJak-STAT signaling pathwayHematopoietic cell lineageMore Pathways >>
Protein Data
Protein Image
 

Reference Data
RefSeq: NP_000591 RefSeq Size: 1125 RefSeq ORF: 639
LocusID: 3569 Cytogenetic: 7p21  
Synonyms : BSF2; HGF; HSF; IFNB2; IL-6
Summary: This gene encodes a cytokine that functions in inflammation and the maturation of B cells. In addition, the encoded protein has been shown to be an endogenous pyrogen capable of inducing fever in people with autoimmune diseases or infections. The protein is primarily produced at sites of acute and chronic inflammation, where it is secreted into the serum and induces a transcriptional inflammatory response through interleukin 6 receptor, alpha. The functioning of this gene is implicated in a wide variety of inflammation-associated disease states, including suspectibility to diabetes mellitus and systemic juvenile rheumatoid arthritis. [provided by RefSeq, Jun 2011].
*: Inventory for certain proteins may be limited due to low expression level. Delivery time may vary from web posted schedule. Contact techsupport@origene.com for specific inventory information
**: DDK-tag is the same as FLAG tag. Flag® is a registered trademark of Sigma-Aldrich

 

bar
Inc 5000 Healthcare Company
All Products by: Title | Price | Category | Popularity | Best Sellers Topselling Products by: Title | Price | Category | Popularity | Favorites
Popular Categories: Popularity | Our Choices | All-Round Favorites | Title Topselling Categories: Popularity | Our Choices | All-Round Favorites | Title

Notice to Non-US Customers

ExclaimationWeb price and delivery time are for direct sales only.

Non-US customers are encouraged to contact our dedicated distributor network for quotes and streamlined ordering/delivery support.

Acknowledge