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Home Recombinant Human Proteins All PRKCE Proteins

PRKCE (NM_005400) Purified Human Protein

Specifications Citations Customer Service Product Documents
Cat. No. Description Datasheet Price Availability*  
TP710186 Purified recombinant protein of Human protein kinase C, epsilon (PRKCE), full length, with C-terminal DDK tag, expressed in sf9, 20ug, 20 ug (Larger pack size?) $399 In Stock
TA50011-100 Clone OTI4C5, Anti-DDK (FLAG) monoclonal antibody $248 In Stock
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OriGene Data
Species:Human Expression Host:Sf9 cells
Expression cDNA Clone or AA Sequence
A DNA sequence from TrueORF clone, RC217702, encoding human full-length PRKCE
Tag:C-terminal DDK Predicted MW:83.5 kDa
Purity:> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration:>50 ug/mL as determined by microplate BCA method
Buffer:50mM Tris-HCl, pH8.0, 100mM glycine, 10% glycerol.
Protein Families: Protein KinaseDruggable Genome
Protein Pathways: Vascular smooth muscle contractionTight junctionFc epsilon RI signaling pathwayFc gamma R-mediated phagocytosisType II diabetes mellitus
Protein Data
Protein Image
 

Reference Data
RefSeq: NP_005391 RefSeq Size: 5537 RefSeq ORF: 2211
LocusID: 5581 Cytogenetic: 2p21  
Synonyms : nPKC-epsilon; PKCE
Summary: Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This kinase has been shown to be involved in many different cellular functions, such as neuron channel activation, apoptosis, cardioprotection from ischemia, heat shock response, as well as insulin exocytosis. Knockout studies in mice suggest that this kinase is important for lipopolysaccharide (LPS)-mediated signaling in activated macrophages and may also play a role in controlling anxiety-like behavior. [provided by RefSeq, Jul 2008].
*: Inventory for certain proteins may be limited due to low expression level. Delivery time may vary from web posted schedule. Contact techsupport@origene.com for specific inventory information
**: DDK-tag is the same as FLAG tag. Flag® is a registered trademark of Sigma-Aldrich

 

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