OriGene Technologies, Inc.
Left ProductsProducts divider ServicesServices divider technologyTechnology divider researchResearch divider TechsupportTechSupport divider AboutAbout Right
 
Home Recombinant Human Proteins All ABCB1 Proteins

ABCB1 (NM_000927) Purified Human Protein

Specifications Citations Customer Service Product Documents
Cat. No. Description Datasheet Price Availability*  
TP710110 Recombinant protein of human ATP-binding cassette, sub-family B (MDR/TAP), member 1 (ABCB1), residues 347-710aa,with C-terminal DDK tag,expressed in sf9 cells, 20 ug (Larger pack size?) $399 In Stock
TA801008 ABCB1 mouse monoclonal antibody,clone 2G6 $379 In Stock
Add to Shopping Cart
spacer
Also for ABCB1 (NM_000927)
cDNA Clone shRNA/siRNA Mass Spec Std Protein Antibody

OriGene Data
Species:Human Expression Host:sf9 cells
Expression cDNA Clone or AA Sequence
A DNA sequence from TrueORF clone, RC216080, encoding the region(Met-Gln347-Tyr710) of Homo sapiens ABCB1
Tag:C-terminal HIS Predicted MW:41 kDa
Purity:> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration:>50 ug/mL as determined by microplate BCA method
Buffer:50mM Tris-HCl, pH8.0, 100mM glycine, 10% glycerol. Store at -80C. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions.
Protein Families: ES Cell Differentiation/IPSTransmembraneDruggable Genome
Protein Pathways: ABC transporters
Protein Data
Protein Image
 

Reference Data
RefSeq: NP_000918 RefSeq Size: 4872 RefSeq ORF: 3843
LocusID: 5243 Cytogenetic: 7q21.12  
Synonyms : ABC20; CD243; CLCS; GP170; MDR1; P-GP; PGY1
Summary: The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is an ATP-dependent drug efflux pump for xenobiotic compounds with broad substrate specificity. It is responsible for decreased drug accumulation in multidrug-resistant cells and often mediates the development of resistance to anticancer drugs. This protein also functions as a transporter in the blood-brain barrier. [provided by RefSeq, Jul 2008].
*: Inventory for certain proteins may be limited due to low expression level. Delivery time may vary from web posted schedule. Contact techsupport@origene.com for specific inventory information
**: DDK-tag is the same as FLAG tag. Flag® is a registered trademark of Sigma-Aldrich

 

bar
Inc 5000 Healthcare Company Copyright © 2014 OriGene Technologies, Inc. All Rights Reserved. Legal Notices.
9620 Medical Center Dr., Suite 200, Rockville, MD 20850 • 1.888.267.4436

Reproduction of any materials from this website is strictly forbidden without permission.

All Products by: Title | Price | Category | Popularity | Best Sellers Topselling Products by: Title | Price | Category | Popularity | Favorites
Popular Categories: Popularity | Our Choices | All-Round Favorites | Title Topselling Categories: Popularity | Our Choices | All-Round Favorites | Title