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Home Recombinant Human Proteins All DCK Proteins

DCK (NM_000788) Purified Human Protein

Specifications Citations Customer Service Product Documents
Cat. No. Description Datasheet Price Availability*  
TP710012 Recombinant protein of human deoxycytidine kinase (DCK), full length, with C-terminal DDK tag,expressed in sf9 cells, 20 ug (Larger pack size?) 399 In Stock
TA502698 DCK mouse monoclonal antibody, clone 16G6 $379 In Stock
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OriGene Data
Species:Human Expression Host:Sf9 cells
Expression cDNA Clone or AA Sequence
A DNA sequence from TrueORF clone, RC210767, encoding human full-length DCK
Tag:C-terminal DDK Predicted MW:30 kDa
Purity:> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration:>50 ug/mL as determined by microplate BCA method
Buffer:50mM Tris-HCl pH8.0, 150mM NaCl, 20% glycerol. Store at -80C. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions.
Protein Families: Druggable Genome
Protein Pathways: Purine metabolismPyrimidine metabolism
Protein Data
Protein Image
 

Reference Data
RefSeq: NP_000779 RefSeq Size: 2460 RefSeq ORF: 783
LocusID: 1633 Cytogenetic: 4q13.3  
Synonyms : MGC117410; MGC138632
Summary: Deoxycytidine kinase (DCK) is required for the phosphorylation of several deoxyribonucleosides and their nucleoside analogs. Deficiency of DCK is associated with resistance to antiviral and anticancer chemotherapeutic agents. Conversely, increased deoxycytidine kinase activity is associated with increased activation of these compounds to cytotoxic nucleoside triphosphate derivatives. DCK is clinically important because of its relationship to drug resistance and sensitivity. [provided by RefSeq, Jul 2008].
*: Inventory for certain proteins may be limited due to low expression level. Delivery time may vary from web posted schedule. Contact techsupport@origene.com for specific inventory information
**: DDK-tag is the same as FLAG tag. Flag® is a registered trademark of Sigma-Aldrich

 

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