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Home Recombinant Human Proteins All IL13 Proteins

IL13 (NM_002188) Purified Human Protein

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Cat. No. Description Datasheet Price Availability*  
TP700054 Recombinant protein of secreted form of human interleukin 13 (IL13), 20 ug (Larger pack size?) $680 In Stock
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OriGene Data
Species:Human Expression Host:HEK293 cells
Expression cDNA Clone or AA Sequence
A DNA sequence from TrueORF clone, RC216947, encoding the mature form (Gly35-Asp146) of human IL13
Tag:N-terminal HIS/DDK Predicted MW:16 kDa
Purity:> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration:>50 ug/mL as determined by microplate BCA method
Buffer:1 x PBS, pH7.4. Store at -80C. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions.
Protein Families: Secreted ProteinTransmembraneDruggable Genome
Protein Pathways: Cytokine-cytokine receptor interactionJak-STAT signaling pathwayFc epsilon RI signaling pathwayAsthma
Protein Data
Protein Image
 

Reference Data
RefSeq: NP_002179 RefSeq Size: 1282 RefSeq ORF: 441
LocusID: 3596 Cytogenetic: 5q31  
Synonyms : IL-13; P600
Summary: This gene encodes an immunoregulatory cytokine produced primarily by activated Th2 cells. This cytokine is involved in several stages of B-cell maturation and differentiation. It up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. This cytokine down-regulates macrophage activity, thereby inhibits the production of pro-inflammatory cytokines and chemokines. This cytokine is found to be critical to the pathogenesis of allergen-induced asthma but operates through mechanisms independent of IgE and eosinophils. This gene, IL3, IL5, IL4, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL4. [provided by RefSeq, Jul 2008].
*: Inventory for certain proteins may be limited due to low expression level. Delivery time may vary from web posted schedule. Contact techsupport@origene.com for specific inventory information
**: DDK-tag is the same as FLAG tag. Flag® is a registered trademark of Sigma-Aldrich

 

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