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Home Recombinant Human Proteins All VAV3 Proteins

VAV3 (NM_006113) Purified Human Protein

Specifications Citations Customer Service Product Documents
Cat. No. Description Datasheet Price Availability*  
TP320550 Recombinant protein of human vav 3 guanine nucleotide exchange factor (VAV3), transcript variant 1, 20 ug (Larger pack size?) 680 In Stock
TA303772 Rabbit monoclonal antibody against Vav3 (Pan)(EP1130Y) $325 In Stock
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Also for VAV3 (NM_006113)
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OriGene Data
Species:Human Expression Host:HEK293 cells
Expression cDNA Clone or AA Sequence
Recombinant protein was produced with TrueORF clone, RC220550. Click on the TrueORF clone link to view cDNA and protein sequences.
Tag:C-terminal MYC/DDK Predicted MW:97.6 kDa
Purity:> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration:>50 ug/mL as determined by microplate BCA method
Buffer:25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Protein Families: Druggable Genome
Protein Pathways: Chemokine signaling pathwayFocal adhesionNatural killer cell mediated cytotoxicityT cell receptor signaling pathwayB cell receptor signaling pathwayFc epsilon RI signaling pathwayMore Pathways >>
Protein Data
Protein Image
 

Reference Data
RefSeq: NP_006104 RefSeq Size: 4768 RefSeq ORF: 2544
LocusID: 10451 Cytogenetic: 1p13.3  
Synonyms : FLJ40431
Summary: This gene is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. This gene product acts as a GEF preferentially for RhoG, RhoA, and to a lesser extent, RAC1, and it associates maximally with the nucleotide-free states of these GTPases. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008].
*: Inventory for certain proteins may be limited due to low expression level. Delivery time may vary from web posted schedule. Contact techsupport@origene.com for specific inventory information
**: DDK-tag is the same as FLAG tag. Flag® is a registered trademark of Sigma-Aldrich

 

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