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Home Recombinant Human Proteins All TNFRSF10B Proteins

TNFRSF10B (NM_147187) Purified Human Protein

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Cat. No. Description Datasheet Price Availability*  
TP319808 Recombinant protein of human tumor necrosis factor receptor superfamily, member 10b (TNFRSF10B), transcript variant 2, 20 ug (Larger pack size?) 680 In Stock
TA305974 Rabbit Polyclonal DR5 Antibody $325 In Stock
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Also for TNFRSF10B (NM_147187)
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OriGene Data
Species:Human Expression Host:HEK293 cells
Expression cDNA Clone or AA Sequence
Recombinant protein was produced with TrueORF clone, RC219808. Click on the TrueORF clone link to view cDNA and protein sequences.
Tag:C-terminal MYC/DDK Predicted MW:39.4 kDa
Purity:> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration:>50 ug/mL as determined by microplate BCA method
Buffer:25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Protein Families: TransmembraneDruggable Genome
Protein Pathways: Cytokine-cytokine receptor interactionp53 signaling pathwayApoptosisNatural killer cell mediated cytotoxicity
Protein Data
Protein Image
 

Reference Data
RefSeq: NP_671716 RefSeq Size: 4073 RefSeq ORF: 1236
LocusID: 8795 Cytogenetic: 8p22  
Synonyms : CD262; DR5; KILLER; KILLER/DR5; TRAIL-R2; TRAILR2; TRICK2; TRICK2A; TRICK2B; TRICKB; ZTNFR9
Summary: The protein encoded by this gene is a member of the TNF-receptor superfamily, and contains an intracellular death domain. This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and transduces an apoptosis signal. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. Two transcript variants encoding different isoforms and one non-coding transcript have been found for this gene. [provided by RefSeq, Mar 2009].
*: Inventory for certain proteins may be limited due to low expression level. Delivery time may vary from web posted schedule. Contact techsupport@origene.com for specific inventory information
**: DDK-tag is the same as FLAG tag. Flag® is a registered trademark of Sigma-Aldrich

 

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