NAALAD2 (NM_005467) Purified Human Protein

Species: Human Expression Host: Human 293HEK cells Expression cDNA Clone and Sequence Recombinant protein was produced with TrueORF clone, RC219582. Click on the TrueORF clone link to view cDNA and protein sequences. Tag: C-terminal MYC/DDK Predicted MW: 83.4 kDa Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining Mass Spec Validation: This protein has been positively validated by MS/MS by Dr. Robert Moritz at The Institute of Systems Biology. Concentration: >50 ug/mL as determined by microplate BCA method Buffer and Storage: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. Store at -80C. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions. Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. Protein Families: TransmembraneDruggable Genome Protein Pathways:

Protein Data

RefSeq: NP_005458	RefSeq Size: 3133	RefSeq ORF: 2223
LocusID: 10003	Cytogenetic: 11q14.3
Synonyms : GCPIII; GPCIII; NAADALASE2; NAALADASE2
Summary: This gene is a member of the N-acetylated alpha-linked acidic dipeptidase (NAALADase) gene family. The representative member of this family is the gene encoding human prostate-specific membrane antigen (PSM), which is a marker of prostatic carcinomas and is the first to be shown to possess NAALADase activity. NAALADase cleaves N-acetyl-L-aspartate-L-glutamate (NAAG), which is a neuropeptide expressed both in the central nervous systems and in the periphery and is thought to function as a neurotransmitter. The product of this gene is a type II integral membrane protein. Transient transfection of this gene confers both NAALADase and dipetidyl peptidase IV activities to mammalian cells. This gene is highly expressed in ovary and testis as well as within discrete brain areas. [provided by RefSeq, Jul 2008].

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Related ORF Clones • Myc-DDK-tagged ORF clone of Homo sapiens N-acetylated alpha-linked acidic dipeptidase 2 (NAALAD2) as transfection-ready DNA • Lenti ORF clone of Human N-acetylated alpha-linked acidic dipeptidase 2 (NAALAD2) , Myc-DDK-tagged • Lenti ORF clone of Human N-acetylated alpha-linked acidic dipeptidase 2 (NAALAD2), mGFP tagged • GFP-tagged ORF clone of Homo sapiens N-acetylated alpha-linked acidic dipeptidase 2 (NAALAD2) as transfection-ready DNA • Myc-DDK-tagged ORF clone of Homo sapiens N-acetylated alpha-linked acidic dipeptidase 2 (NAALAD2) as 200 ug transfection-ready DNA Related Lysate from OriGene • Transient overexpression lysate of N-acetylated alpha-linked acidic dipeptidase 2 (NAALAD2) Anti-Tag Antibodies & WB Reagent • Anti-Tag Antibodies • Western Blot Reagent shRNA • NAALAD2 - Human, 4 unique 29mer shRNA constructs in retroviral RFP vector • NAALAD2 - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector • Naalad2 - Mouse, 4 unique 29mer shRNA constructs in retroviral GFP vector • NAALAD2 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector • Naalad2 - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector Related Primer Pair qSTAR qPCR primer pairs against Homo sapiens gene NAALAD2

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Protein	Full Length Protein A domain of the protein Description of domain...
Tag	C-fusion N-fusion     Tag Description:
DNA or protein sequence of the final product
Preferred Expression Host	HEK293 E. coli Insect Cells Yeast
The main application with the purified protein	R&D reagent Cell-based Assay Animal Study Other, please specify:
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