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Home Recombinant Human Proteins All LCK Proteins

LCK (NM_005356) Purified Human Protein

Specifications Citations Customer Service Product Documents
Cat. No. Description Datasheet Price Availability*  
TP319375 Recombinant protein of human lymphocyte-specific protein tyrosine kinase (LCK), transcript variant 2, 20 ug (Larger pack size?) 680 In Stock
TA300455 Rabbit Monoclonal Antibody against LCK (Clone Y123) $325 3-7 Days
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OriGene Data
Species:Human Expression Host:HEK293 cells
Expression cDNA Clone or AA Sequence
Recombinant protein was produced with TrueORF clone, RC219375. Click on the TrueORF clone link to view cDNA and protein sequences.
Tag:C-terminal MYC/DDK Predicted MW:57.8 kDa
Purity:> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration:>50 ug/mL as determined by microplate BCA method
Buffer:25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Protein Families: Protein KinaseStem cell - PluripotencyDruggable Genome
Protein Pathways: Natural killer cell mediated cytotoxicityT cell receptor signaling pathwayPrimary immunodeficiency
Protein Data
Protein Image
 

Reference Data
RefSeq: NP_005347 RefSeq Size: 2032 RefSeq ORF: 1530
LocusID: 3932 Cytogenetic: 1p34.3  
Synonyms : IMD22; LSK; p56lck; pp58lck; YT16
Summary: This gene is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein is a key signaling molecule in the selection and maturation of developing T-cells. It contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to the plasma membrane and pericentrosomal vesicles, and binds to cell surface receptors, including CD4 and CD8, and other signaling molecules. Multiple alternatively spliced variants, encoding the same protein, have been described. [provided by RefSeq, Jul 2008].
*: Inventory for certain proteins may be limited due to low expression level. Delivery time may vary from web posted schedule. Contact techsupport@origene.com for specific inventory information
**: DDK-tag is the same as FLAG tag. Flag® is a registered trademark of Sigma-Aldrich

 

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