Promotion ends on May 1st.
Also for APRT (NM_000485)
|Expression cDNA Clone or AA Sequence
Recombinant protein was produced with TrueORF clone, RC216874
. Click on the TrueORF clone link to view cDNA and protein sequences.
||Predicted MW:||19.4 kDa|
|Purity:||> 80% as determined by SDS-PAGE and Coomassie blue staining|
|Concentration:||>50 ug/mL as determined by microplate BCA method|
|Buffer:||25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.|
||Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
||Purine metabolismMetabolic pathways
||RefSeq Size: 807
||RefSeq ORF: 543|
|Synonyms : AMP; APRTD|
|Summary: Adenine phosphoribosyltransferase belongs to the purine/pyrimidine phosphoribosyltransferase family. A conserved feature of this gene is the distribution of CpG dinucleotides. This enzyme catalyzes the formation of AMP and inorganic pyrophosphate from adenine and 5-phosphoribosyl-1-pyrophosphate (PRPP). It also produces adenine as a by-product of the polyamine biosynthesis pathway. A homozygous deficiency in this enzyme causes 2,8-dihydroxyadenine urolithiasis. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]. |
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**: DDK-tag is the same as FLAG tag. Flag® is a registered trademark of Sigma-Aldrich