BAG6 (NM_080703) Purified Human Protein

Species: Human Expression Host: Human 293HEK cells Expression cDNA Clone and Sequence Recombinant protein was produced with TrueORF clone, RC215646. Click on the TrueORF clone link to view cDNA and protein sequences. Tag: C-terminal MYC/DDK Predicted MW: 118.5 kDa Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining Mass Spec Validation: This protein has been positively validated by MS/MS by Dr. Robert Moritz at The Institute of Systems Biology. Concentration: >50 ug/mL as determined by microplate BCA method Buffer and Storage: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. Store at -80C. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions. Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. Protein Families: Stem cell - PluripotencyDruggable Genome Protein Pathways:

Protein Data

RefSeq: NP_542434	RefSeq Size: 3755	RefSeq ORF: 3381
LocusID: 7917	Cytogenetic: 6p21.3
Synonyms : BAG-6; BAT3; D6S52E; G3
Summary: This gene was first characterized as part of a cluster of genes located within the human major histocompatibility complex class III region. This gene encodes a nuclear protein that is cleaved by caspase 3 and is implicated in the control of apoptosis. In addition, the protein forms a complex with E1A binding protein p300 and is required for the acetylation of p53 in response to DNA damage. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

Researchers who bought this clone have also purchased:

Related ORF Clones • Myc-DDK-tagged ORF clone of Homo sapiens BCL2-associated athanogene 6 (BAG6), transcript variant 3 as transfection-ready DNA • GFP-tagged ORF clone of Homo sapiens BCL2-associated athanogene 6 (BAG6), transcript variant 3 as transfection-ready DNA • Myc-DDK-tagged ORF clone of Homo sapiens BCL2-associated athanogene 6 (BAG6), transcript variant 3 as 200 ug transfection-ready DNA Related Lysate from OriGene • Transient overexpression lysate of HLA-B associated transcript 3 (BAT3), transcript variant 3 Anti-Tag Antibodies & WB Reagent • Anti-Tag Antibodies • Western Blot Reagent shRNA • BAT3 - Human, 4 unique 29mer shRNA constructs in retroviral RFP vector • BAT3 - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector • Bat3 - Mouse, 4 unique 29mer shRNA constructs in retroviral GFP vector • BAT3 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector • Bat3 - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector

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Protein	Full Length Protein A domain of the protein Description of domain...
Tag	C-fusion N-fusion     Tag Description:
DNA or protein sequence of the final product
Preferred Expression Host	HEK293 E. coli Insect Cells Yeast
The main application with the purified protein	R&D reagent Cell-based Assay Animal Study Other, please specify:
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