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Home Recombinant Human Proteins All PVRL2 Proteins

PVRL2 (NM_001042724) Purified Human Protein

Specifications Citations Customer Service Product Documents
Cat. No. Description Datasheet Price Availability*  
TP313693 Recombinant protein of human poliovirus receptor-related 2 (herpesvirus entry mediator B) (PVRL2), transcript variant delta, 20 ug (Larger pack size?) 680 In Stock
TA307993 Rabbit polyclonal antibody to PVRL2(CD112) (poliovirus receptor-related 2 (herpesvirus entry mediator B)) $325 3-7 Days
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OriGene Data
Species:Human Expression Host:HEK293 cells
Expression cDNA Clone or AA Sequence
Recombinant protein was produced with TrueORF clone, RC213693. Click on the TrueORF clone link to view cDNA and protein sequences.
Tag:C-terminal MYC/DDK Predicted MW:54.4 kDa
Purity:> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration:>50 ug/mL as determined by microplate BCA method
Buffer:25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Protein Families: TransmembraneDruggable Genome
Protein Pathways: Cell adhesion molecules (CAMs)Adherens junction
Protein Data
Protein Image
 

Reference Data
RefSeq: NP_001036189 RefSeq Size: 2869 RefSeq ORF: 1617
LocusID: 5819 Cytogenetic: 19q13.2  
Synonyms : CD112; HVEB; PRR2; PVRR2
Summary: This gene encodes a single-pass type I membrane glycoprotein with two Ig-like C2-type domains and an Ig-like V-type domain. This protein is one of the plasma membrane components of adherens junctions. It also serves as an entry for certain mutant strains of herpes simplex virus and pseudorabies virus, and it is involved in cell to cell spreading of these viruses. Variations in this gene have been associated with differences in the severity of multiple sclerosis. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008].
*: Inventory for certain proteins may be limited due to low expression level. Delivery time may vary from web posted schedule. Contact techsupport@origene.com for specific inventory information
**: DDK-tag is the same as FLAG tag. Flag® is a registered trademark of Sigma-Aldrich

 

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