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Home Recombinant Human Proteins All NANOS2 Proteins

NANOS2 (NM_001029861) Purified Human Protein

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Cat. No. Description Datasheet Price Availability*  
TP312815 Recombinant protein of human nanos homolog 2 (Drosophila) (NANOS2), 20 ug (Larger pack size?) $680 In Stock
TA306592 Rabbit Polyclonal Nanos2 Antibody $325 3-7 Days
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Also for NANOS2 (NM_001029861)
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OriGene Data
Species:Human Expression Host:HEK293 cells
Expression cDNA Clone or AA Sequence
Recombinant protein was produced with TrueORF clone, RC212815. Click on the TrueORF clone link to view cDNA and protein sequences.
Tag:C-terminal MYC/DDK Predicted MW:15 kDa
Purity:> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration:>50 ug/mL as determined by microplate BCA method
Buffer:25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Protein Families:
Protein Pathways:
Protein Data
Protein Image
 

Reference Data
RefSeq: NP_001025032 RefSeq Size: 1579 RefSeq ORF: 417
LocusID: 339345 Cytogenetic: 19q13.32  
Synonyms : NOS2
Summary: Plays a key role in the sexual differentiation of germ cells by promoting the male fate but suppressing the female fate. Represses the female fate pathways by suppressing meiosis, which in turn results in the promotion of the male fate. Maintains the suppression of meiosis by preventing STRA8 expression, which is required for premeiotic DNA replication, after CYP26B1 is decreased. Regulates the localization of the CCR4-NOT deadenylation complex to P-bodies and plays a role in recruiting the complex to trigger the degradation of mRNAs involved in meiosis. Required for the maintenance of the spermatogonial stem cell population. Not essential for the assembly of P-bodies but is required for the maintenance of their normal state. [UniProtKB/Swiss-Prot Function]
*: Inventory for certain proteins may be limited due to low expression level. Delivery time may vary from web posted schedule. Contact techsupport@origene.com for specific inventory information
**: DDK-tag is the same as FLAG tag. Flag® is a registered trademark of Sigma-Aldrich

 

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