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Home Recombinant Human Proteins All PDGFRA Proteins

PDGFRA (NM_006206) Purified Human Protein

Specifications Citations Customer Service Product Documents
Cat. No. Description Datasheet Price Availability*  
TP311740 Recombinant protein of human platelet-derived growth factor receptor, alpha polypeptide (PDGFRA), 20 ug (Larger pack size?) 680 In Stock
TA307172 Rabbit monoclonal antibody against PDGF Receptor alpha Phospho (pY720)(clone EP2478) (Phospho-Specific) $325 3-7 Days
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Also for PDGFRA (NM_006206)
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OriGene Data
Species:Human Expression Host:HEK293 cells
Expression cDNA Clone or AA Sequence
Recombinant protein was produced with TrueORF clone, RC211740. Click on the TrueORF clone link to view cDNA and protein sequences.
Tag:C-terminal MYC/DDK Predicted MW:120.3 kDa
Purity:> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration:>50 ug/mL as determined by microplate BCA method
Buffer:25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Protein Families: Protein KinaseES Cell Differentiation/IPSTransmembraneDruggable Genome
Protein Pathways: MAPK signaling pathwayCalcium signaling pathwayCytokine-cytokine receptor interactionEndocytosisFocal adhesionGap junctionMore Pathways >>
Protein Data
Protein Image
 

Reference Data
RefSeq: NP_006197 RefSeq Size: 6405 RefSeq ORF: 3270
LocusID: 5156 Cytogenetic: 4q12  
Synonyms : CD140A; PDGFR-2; PDGFR2; RHEPDGFRA
Summary: This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies suggest that this gene plays a role in organ development, wound healing, and tumor progression. Mutations in this gene have been associated with idiopathic hypereosinophilic syndrome, somatic and familial gastrointestinal stromal tumors, and a variety of other cancers. [provided by RefSeq, Mar 2012].
*: Inventory for certain proteins may be limited due to low expression level. Delivery time may vary from web posted schedule. Contact techsupport@origene.com for specific inventory information
**: DDK-tag is the same as FLAG tag. Flag® is a registered trademark of Sigma-Aldrich

 

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