SAA1 (NM_000331) Purified Human Protein

Species: Human Expression Host: Human 293HEK cells Expression cDNA Clone and Sequence Recombinant protein was produced with TrueORF clone, RC210664. Click on the TrueORF clone link to view cDNA and protein sequences. Tag: C-terminal MYC/DDK Predicted MW: 13.4 kDa Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining Mass Spec Validation: This protein has been positively validated by MS/MS by Dr. Robert Moritz at The Institute of Systems Biology. Concentration: >50 ug/mL as determined by microplate BCA method Buffer and Storage: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. Store at -80C. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions. Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. Protein Families: Protein Pathways:

Protein Data

RefSeq: NP_000322	RefSeq Size: 722	RefSeq ORF: 369
LocusID: 6288	Cytogenetic: 11p15.1
Synonyms : PIG4; SAA; SAA2; TP53I4
Summary: This gene encodes a member of the serum amyloid A family of apolipoproteins. The encoded protein is a major acute phase protein that is highly expressed in response to inflammation and tissue injury. This protein also plays an important role in HDL metabolism and cholesterol homeostasis. High levels of this protein are associated with chronic inflammatory diseases including atherosclerosis, rheumatoid arthritis, Alzheimer's disease and Crohn's disease. This protein may also be a potential biomarker for certain tumors. Alternate splicing results in multiple transcript variants that encode the same protein. A pseudogene of this gene is found on chromosome 11.[provided by RefSeq, Jun 2012].

Researchers who bought this clone have also purchased:

Related ORF Clones • Myc-DDK-tagged ORF clone of Homo sapiens serum amyloid A1 (SAA1), transcript variant 1 as transfection-ready DNA • Lenti ORF clone of Human serum amyloid A1 (SAA1), transcript variant 1 , Myc-DDK-tagged • Lenti ORF clone of Human serum amyloid A1 (SAA1), transcript variant 1, mGFP tagged • GFP-tagged ORF clone of Homo sapiens serum amyloid A1 (SAA1), transcript variant 1 as transfection-ready DNA • Myc-DDK-tagged ORF clone of Homo sapiens serum amyloid A1 (SAA1), transcript variant 1 as 200 ug transfection-ready DNA Related Lysate from OriGene • Transient overexpression lysate of serum amyloid A1 (SAA1), transcript variant 1 Anti-Tag Antibodies & WB Reagent • Anti-Tag Antibodies • Western Blot Reagent shRNA • SAA1 - Human, 4 unique 29mer shRNA constructs in retroviral RFP vector • SAA1 - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector • Saa1 - Mouse, 4 unique 29mer shRNA constructs in retroviral GFP vector • SAA1 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector • Saa1 - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector Related Primer Pair qSTAR qPCR primer pairs against Homo sapiens gene SAA1

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Protein	Full Length Protein A domain of the protein Description of domain...
Tag	C-fusion N-fusion     Tag Description:
DNA or protein sequence of the final product
Preferred Expression Host	HEK293 E. coli Insect Cells Yeast
The main application with the purified protein	R&D reagent Cell-based Assay Animal Study Other, please specify:
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