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Home Recombinant Human Proteins All F2 Proteins

F2 (NM_000506) Purified Human Protein

Specifications Citations Customer Service Product Documents
Cat. No. Description Datasheet Price Availability*  
TP308589 Recombinant protein of human coagulation factor II (thrombin) (F2), 20 ug (Larger pack size?) 680 In Stock
TA313852 Rabbit polyclonal Prothrombin / THRB (AP2, Cleaved-Arg327) antibody $325 In Stock
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OriGene Data
Species:Human Expression Host:HEK293 cells
Expression cDNA Clone or AA Sequence
Recombinant protein was produced with TrueORF clone, RC208589. Click on the TrueORF clone link to view cDNA and protein sequences.
Tag:C-terminal MYC/DDK Predicted MW:67.5 kDa
Purity:> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration:>50 ug/mL as determined by microplate BCA method
Buffer:25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Protein Families: Secreted ProteinProteaseDruggable Genome
Protein Pathways: Neuroactive ligand-receptor interactionComplement and coagulation cascadesRegulation of actin cytoskeleton
Protein Data
Protein Image
 

Reference Data
RefSeq: NP_000497 RefSeq Size: 1997 RefSeq ORF: 1869
LocusID: 2147 Cytogenetic: 11p11  
Synonyms : PT; RPRGL2; THPH1
Summary: Coagulation factor II is proteolytically cleaved to form thrombin in the first step of the coagulation cascade which ultimately results in the stemming of blood loss. F2 also plays a role in maintaining vascular integrity during development and postnatal life. Mutations in F2 leads to various forms of thrombosis and dysprothrombinemia. [provided by RefSeq, Jul 2008].
*: Inventory for certain proteins may be limited due to low expression level. Delivery time may vary from web posted schedule. Contact techsupport@origene.com for specific inventory information
**: DDK-tag is the same as FLAG tag. Flag® is a registered trademark of Sigma-Aldrich

 

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