TBC1D1 (NM_015173) Purified Human Protein

Species: Human Expression Host: Human 293HEK cells Expression cDNA Clone and Sequence Recombinant protein was produced with TrueORF clone, RC207980. Click on the TrueORF clone link to view cDNA and protein sequences. Tag: C-terminal MYC/DDK Predicted MW: 132.9 kDa Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining Mass Spec Validation: This protein has been positively validated by MS/MS by Dr. Robert Moritz at The Institute of Systems Biology. Concentration: >50 ug/mL as determined by microplate BCA method Buffer and Storage: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. Store at -80C. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions. Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. Protein Families: Druggable Genome Protein Pathways:

Protein Data

RefSeq: NP_055988	RefSeq Size: 5688	RefSeq ORF: 3507
LocusID: 23216	Cytogenetic: 4p14
Synonyms : TBC; TBC1
Summary: TBC1D1 is the founding member of a family of proteins sharing a 180- to 200-amino acid TBC domain presumed to have a role in regulating cell growth and differentiation. These proteins share significant homology with TRE2 (USP6; MIM 604334), yeast Bub2, and CDC16 (MIM 603461) (White et al., 2000 [PubMed 10965142]).[supplied by OMIM, Mar 2008].

Researchers who bought this clone have also purchased:

Related ORF Clones • Myc-DDK-tagged ORF clone of Homo sapiens TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1 (TBC1D1) as transfection-ready DNA • GFP-tagged ORF clone of Homo sapiens TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1 (TBC1D1) as transfection-ready DNA Related Lysate from OriGene • Transient overexpression lysate of TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1 (TBC1D1) Validated Antibodies • TBC1 / TBC1D1 Rabbit Polyclonal (C-Terminus) Antibody • Rabbit Polyclonal TBC1D1 Antibody Anti-Tag Antibodies & WB Reagent • Anti-Tag Antibodies • Western Blot Reagent shRNA • TBC1D1 - Human, 4 unique 29mer shRNA constructs in retroviral RFP vector • TBC1D1 - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector • Tbc1d1 - Mouse, 4 unique 29mer shRNA constructs in retroviral GFP vector • TBC1D1 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector • Tbc1d1 - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector Related Primer Pair qSTAR qPCR primer pairs against Homo sapiens gene TBC1D1

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Protein	Full Length Protein A domain of the protein Description of domain...
Tag	C-fusion N-fusion     Tag Description:
DNA or protein sequence of the final product
Preferred Expression Host	HEK293 E. coli Insect Cells Yeast
The main application with the purified protein	R&D reagent Cell-based Assay Animal Study Other, please specify:
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