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Home Recombinant Human Proteins All ACE Proteins

ACE (NM_152831) Purified Human Protein

Specifications Citations Customer Service Product Documents
Cat. No. Description Datasheet Price Availability*  
TP305392 Recombinant protein of human angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 (ACE), transcript variant 3, 20 ug (Larger pack size?) 680 In Stock
TA303478 Rabbit monoclonal antibody against ACE (angiotensin converting enzyme) (EPR2757 ) $325 3-7 Days
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OriGene Data
Species:Human Expression Host:HEK293 cells
Expression cDNA Clone or AA Sequence
Recombinant protein was produced with TrueORF clone, RC205392. Click on the TrueORF clone link to view cDNA and protein sequences.
Tag:C-terminal MYC/DDK Predicted MW:84.4
Purity:> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration:>50 ug/mL as determined by microplate BCA method
Buffer:25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Protein Families: Secreted ProteinES Cell Differentiation/IPSTransmembraneProteaseDruggable Genome
Protein Pathways: Renin-angiotensin systemHypertrophic cardiomyopathy (HCM)
Protein Data
Protein Image
 

Reference Data
RefSeq: NP_690044 RefSeq Size: 4863 RefSeq ORF: 2219
LocusID: 1636 Cytogenetic: 17q23.3  
Synonyms : DCP, ACE1, DCP1, CD143, MGC26566
Summary: This gene encodes an enzyme involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance. This enzyme plays a key role in the renin-angiotensin system. Many studies have associated the presence or absence of a 287 bp Alu repeat element in this gene with the levels of circulating enzyme or cardiovascular pathophysiologies. Multiple alternatively spliced transcript variants encoding different isoforms have been identified, and two most abundant spliced variants encode the somatic form and the testicular form, respectively, that are equally active. [provided by RefSeq, May
*: Inventory for certain proteins may be limited due to low expression level. Delivery time may vary from web posted schedule. Contact techsupport@origene.com for specific inventory information
**: DDK-tag is the same as FLAG tag. Flag® is a registered trademark of Sigma-Aldrich

 

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