Promotion ends on May 1st.
Also for EDNRB (NM_000115)
|Expression cDNA Clone or AA Sequence
Recombinant protein was produced with TrueORF clone, RC204899
. Click on the TrueORF clone link to view cDNA and protein sequences.
||Predicted MW:||46.9 kDa|
|Purity:||> 80% as determined by SDS-PAGE and Coomassie blue staining|
|Concentration:||>50 ug/mL as determined by microplate BCA method|
|Buffer:||25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.|
||Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
||Calcium signaling pathwayNeuroactive ligand-receptor interactionMelanogenesis
||RefSeq Size: 4286
||RefSeq ORF: 1329|
|Synonyms : ABCDS; ET-B; ET-BR; ETB; ETBR; ETRB; HSCR; HSCR2; WS4A|
|Summary: The protein encoded by this gene is a G protein-coupled receptor which activates a phosphatidylinositol-calcium second messenger system. Its ligand, endothelin, consists of a family of three potent vasoactive peptides: ET1, ET2, and ET3. Studies suggest that the multigenic disorder, Hirschsprung disease type 2, is due to mutations in the endothelin receptor type B gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan |
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**: DDK-tag is the same as FLAG tag. Flag® is a registered trademark of Sigma-Aldrich