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EDNRB (NM_000115) Purified Human Protein

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Cat. No. Description Datasheet Price Availability*  
TP304899 Recombinant protein of human endothelin receptor type B (EDNRB), transcript variant 1, 20 ug (Larger pack size?) 680
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OriGene Data
Species:Human Expression Host:HEK293 cells
Expression cDNA Clone or AA Sequence
Recombinant protein was produced with TrueORF clone, RC204899. Click on the TrueORF clone link to view cDNA and protein sequences.
Tag:C-terminal MYC/DDK Predicted MW:46.9 kDa
Purity:> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration:>50 ug/mL as determined by microplate BCA method
Buffer:25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Protein Families: GPCRTransmembraneDruggable Genome
Protein Pathways: Calcium signaling pathwayNeuroactive ligand-receptor interactionMelanogenesis
Protein Data
Protein Image

Reference Data
RefSeq: NP_000106 RefSeq Size: 4286 RefSeq ORF: 1329
LocusID: 1910 Cytogenetic: 13q22  
Summary: The protein encoded by this gene is a G protein-coupled receptor which activates a phosphatidylinositol-calcium second messenger system. Its ligand, endothelin, consists of a family of three potent vasoactive peptides: ET1, ET2, and ET3. Studies suggest that the multigenic disorder, Hirschsprung disease type 2, is due to mutations in the endothelin receptor type B gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2011].
*: Inventory for certain proteins may be limited due to low expression level. Delivery time may vary from web posted schedule. Contact techsupport@origene.com for specific inventory information
**: DDK-tag is the same as FLAG tag. Flag® is a registered trademark of Sigma-Aldrich


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