FXN (NM_000144) Purified Human Protein

Species: Human Expression Host: Human 293HEK cells Expression cDNA Clone and Sequence Recombinant protein was produced with TrueORF clone, RC204880. Click on the TrueORF clone link to view cDNA and protein sequences. Tag: C-terminal MYC/DDK Predicted MW: 18.8 kDa Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining Mass Spec Validation: This protein has been positively validated by MS/MS by Dr. Robert Moritz at The Institute of Systems Biology. Concentration: >50 ug/mL as determined by microplate BCA method Buffer and Storage: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. Store at -80C. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions. Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. Protein Families: Druggable Genome Protein Pathways:

Protein Data

RefSeq: NP_000135	RefSeq Size: 2262	RefSeq ORF: 633
LocusID: 2395	Cytogenetic: 9q21.11
Synonyms : CyaY; FA; FARR; FRDA; X25
Summary: This nuclear gene encodes a mitochondrial protein which belongs to FRATAXIN family. The protein functions in regulating mitochondrial iron transport and respiration. The expansion of intronic trinucleotide repeat GAA results in Friedreich ataxia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2009].

Researchers who bought this clone have also purchased:

Related ORF Clones • Myc-DDK-tagged ORF clone of Homo sapiens frataxin (FXN), nuclear gene encoding mitochondrial protein, transcript variant 1 as transfection-ready DNA • Lenti ORF clone of Human frataxin (FXN), nuclear gene encoding mitochondrial protein, transcript variant 1 , Myc-DDK-tagged • Lenti ORF clone of Human frataxin (FXN), nuclear gene encoding mitochondrial protein, transcript variant 1, mGFP tagged • GFP-tagged ORF clone of Homo sapiens frataxin (FXN), nuclear gene encoding mitochondrial protein, transcript variant 1 as transfection-ready DNA Related Lysate from OriGene • Transient overexpression lysate of frataxin (FXN), nuclear gene encoding mitochondrial protein, transcript variant 1 Validated Antibodies • Purified FXN (Frataxin) mouse monoclonal antibody, Clone 1C12 • Purified FXN (Frataxin) mouse monoclonal antibody, Clone 1F2 • Purified FXN (Frataxin) mouse monoclonal antibody, Clone 3B6 • Purified FXN (Frataxin) mouse monoclonal antibody, clone 3C7 • Purified FXN (Frataxin) mouse monoclonal antibody, Clone 4G4 • Purified FXN (Frataxin) mouse monoclonal antibody, Clone 3F3 • Purified FXN (Frataxin) mouse monoclonal antibody, Clone 3C3 • Purified FXN (Frataxin) mouse monoclonal antibody, Clone 4D7 • Rabbit Monoclonal antibody against Frataxin (FXN) • Purified Rabbit Polyclonal Antibody against FXN (C-term) • Carrier-free (BSA/glycerol-free) FXN mouse monoclonal antibody,clone 1C12 • Carrier-free (BSA/glycerol-free) FXN mouse monoclonal antibody,clone 1F2 • Carrier-free (BSA/glycerol-free) FXN mouse monoclonal antibody,clone 3B6 • Carrier-free (BSA/glycerol-free) FXN mouse monoclonal antibody,clone 3C7 • Carrier-free (BSA/glycerol-free) FXN mouse monoclonal antibody,clone 4G4 • Carrier-free (BSA/glycerol-free) FXN mouse monoclonal antibody,clone 3F3 • Carrier-free (BSA/glycerol-free) FXN mouse monoclonal antibody,clone 3C3 • Carrier-free (BSA/glycerol-free) FXN mouse monoclonal antibody,clone 4D7 Anti-Tag Antibodies & WB Reagent • Anti-Tag Antibodies • Western Blot Reagent shRNA • FXN - Human, 4 unique 29mer shRNA constructs in retroviral RFP vector • FXN - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector • Fxn - Mouse, 4 unique 29mer shRNA constructs in retroviral GFP vector • FXN - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector • Fxn - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector Related Primer Pair qSTAR qPCR primer pairs against Homo sapiens gene FXN

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Protein	Full Length Protein A domain of the protein Description of domain...
Tag	C-fusion N-fusion     Tag Description:
DNA or protein sequence of the final product
Preferred Expression Host	HEK293 E. coli Insect Cells Yeast
The main application with the purified protein	R&D reagent Cell-based Assay Animal Study Other, please specify:
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