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Home Recombinant Human Proteins All BACE2 Proteins

BACE2 (NM_012105) Purified Human Protein

Specifications Citations Customer Service Product Documents
Cat. No. Description Datasheet Price Availability*  
TP304860 Recombinant protein of human beta-site APP-cleaving enzyme 2 (BACE2), transcript variant a, 20 ug (Larger pack size?) $680 In Stock
TA306031 Rabbit Polyclonal BACE2 Antibody $325 In Stock
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Also for BACE2 (NM_012105)
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OriGene Data
Species:Human Expression Host:HEK293
Expression cDNA Clone or AA Sequence
Recombinant protein was produced with TrueORF clone, RC204860. Click on the TrueORF clone link to view cDNA and protein sequences.
Tag:C-terminal MYC/DDK Predicted MW:49.8 kDa
Purity:> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration:>50 ug/mL as determined by microplate BCA method
Buffer:25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Protein Families: TransmembraneProteaseDruggable Genome
Protein Pathways: Alzheimer's disease
Protein Data
Protein Image
 

Reference Data
RefSeq: NP_036237 RefSeq Size: 2993 RefSeq ORF: 1557
LocusID: 25825 Cytogenetic: 21q22.3  
Synonyms : AEPLC; ALP56; ASP1; ASP21; BAE2; CDA13; CEAP1; DRAP
Summary: This gene encodes an integral membrane glycoprotein that functions as an aspartic protease. The encoded protein cleaves amyloid precursor protein into amyloid beta peptide, which is a critical step in the etiology of Alzheimer's disease and Down syndrome. The protein precursor is further processed into an active mature peptide. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013].
*: Inventory for certain proteins may be limited due to low expression level. Delivery time may vary from web posted schedule. Contact techsupport@origene.com for specific inventory information
**: DDK-tag is the same as FLAG tag. Flag® is a registered trademark of Sigma-Aldrich

 

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