Promotion ends on May 1st.
Also for ITM2B (NM_021999)
|Expression cDNA Clone or AA Sequence
Recombinant protein was produced with TrueORF clone, RC202377
. Click on the TrueORF clone link to view cDNA and protein sequences.
||Predicted MW:||30.2 kDa|
|Purity:||> 80% as determined by SDS-PAGE and Coomassie blue staining|
|Mass Spec Validation:
||This protein has been positively validated by MS/MS by Dr. Robert Moritz at The Institute of Systems Biology.
|Concentration:||>50 ug/mL as determined by microplate BCA method|
|Buffer:||25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.|
||Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
||RefSeq Size: 1896
||RefSeq ORF: 801|
|Synonyms : ABRI; BRI; BRI2; BRICD2B; E25B; E3-16; FBD; imBRI2|
|Summary: Amyloid precursor proteins are processed by beta-secretase and gamma-secretase to produce beta-amyloid peptides which form the characteristic plaques of Alzheimer disease. This gene encodes a transmembrane protein which is processed at the C-terminus by furin or furin-like proteases to produce a small secreted peptide which inhibits the deposition of beta-amyloid. Mutations which result in extension of the C-terminal end of the encoded protein, thereby increasing the size of the secreted peptide, are associated with two neurogenerative diseases, familial British dementia and familial Danish dementia. [provided by RefSeq, Oct 2009]. |
*: Inventory for certain proteins may be limited due to low expression level. Delivery time may vary from web posted schedule. Contact firstname.lastname@example.org
for specific inventory information
**: DDK-tag is the same as FLAG tag. Flag® is a registered trademark of Sigma-Aldrich