PGD (NM_002631) Purified Human Protein

Species: Human Expression Host: Human 293HEK cells Expression cDNA Clone and Sequence Recombinant protein was produced with TrueORF clone, RC201729. Click on the TrueORF clone link to view cDNA and protein sequences. Tag: C-terminal MYC/DDK Predicted MW: 53 kDa Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining Mass Spec Validation: This protein has been positively validated by MS/MS by Dr. Robert Moritz at The Institute of Systems Biology. Concentration: >50 ug/mL as determined by microplate BCA method Buffer and Storage: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. Store at -80C. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions. Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. Protein Families: Protein Pathways: Pentose phosphate pathwayGlutathione metabolismMetabolic pathways

Protein Data

RefSeq: NP_002622	RefSeq Size: 1937	RefSeq ORF: 1452
LocusID: 5226	Cytogenetic: 1p36.22
Synonyms : 6PGD
Summary: 6-phosphogluconate dehydrogenase is the second dehydrogenase in the pentose phosphate shunt. Deficiency of this enzyme is generally asymptomatic, and the inheritance of this disorder is autosomal dominant. Hemolysis results from combined deficiency of 6-phosphogluconate dehydrogenase and 6-phosphogluconolactonase suggesting a synergism of the two enzymopathies. [provided by RefSeq, Jul 2008].

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Related ORF Clones • Myc-DDK-tagged ORF clone of Homo sapiens phosphogluconate dehydrogenase (PGD) as transfection-ready DNA • Lenti ORF clone of Human phosphogluconate dehydrogenase (PGD), mGFP tagged • Lenti ORF clone of Human phosphogluconate dehydrogenase (PGD) , Myc-DDK-tagged • GFP-tagged ORF clone of Homo sapiens phosphogluconate dehydrogenase (PGD) as transfection-ready DNA Related Lysate from OriGene • Transient overexpression lysate of phosphogluconate dehydrogenase (PGD) Validated Antibodies • Rabbit polyclonal anti-PGD antibody • Rabbit Polyclonal antibody to PGD (phosphogluconate dehydrogenase) • Purified PGD mouse monoclonal antibody,clone 2A5 • Carrier-free (BSA/glycerol-free) PGD mouse monoclonal antibody,clone 2A5 Anti-Tag Antibodies & WB Reagent • Anti-Tag Antibodies • Western Blot Reagent shRNA • PGD - Human, 4 unique 29mer shRNA constructs in retroviral RFP vector • PGD - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector • Pgd - Mouse, 4 unique 29mer shRNA constructs in retroviral GFP vector • PGD - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector • Pgd - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector Related Primer Pair qSTAR qPCR primer pairs against Homo sapiens gene PGD

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Protein	Full Length Protein A domain of the protein Description of domain...
Tag	C-fusion N-fusion     Tag Description:
DNA or protein sequence of the final product
Preferred Expression Host	HEK293 E. coli Insect Cells Yeast
The main application with the purified protein	R&D reagent Cell-based Assay Animal Study Other, please specify:
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