PARK7 (NM_007262) Purified Human Protein

Species: Human Expression Host: Human 293HEK cells Expression cDNA Clone and Sequence Recombinant protein was produced with TrueORF clone, RC201645. Click on the TrueORF clone link to view cDNA and protein sequences. Tag: C-terminal MYC/DDK Predicted MW: 19.7 kDa Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining Mass Spec Validation: This protein has been positively validated by MS/MS by Dr. Robert Moritz at The Institute of Systems Biology. Concentration: >50 ug/mL as determined by microplate BCA method Buffer and Storage: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. Store at -80C. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions. Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. Protein Families: ProteaseDruggable Genome Protein Pathways: Parkinson's disease

Protein Data

RefSeq: NP_009193	RefSeq Size: 906	RefSeq ORF: 570
LocusID: 11315	Cytogenetic: 1p36.23
Synonyms : DJ-1; DJ1
Summary: The product of this gene belongs to the peptidase C56 family of proteins. It acts as a positive regulator of androgen receptor-dependent transcription. It may also function as a redox-sensitive chaperone, as a sensor for oxidative stress, and it apparently protects neurons against oxidative stress and cell death. Defects in this gene are the cause of autosomal recessive early-onset Parkinson disease 7. Two transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq, Jul 2008].

Researchers who bought this clone have also purchased:

Related ORF Clones • Myc-DDK-tagged ORF clone of Homo sapiens Parkinson disease (autosomal recessive, early onset) 7 (PARK7), transcript variant 1 as transfection-ready DNA • Lenti ORF clone of Human Parkinson disease (autosomal recessive, early onset) 7 (PARK7), transcript variant 1 , Myc-DDK-tagged • Lenti ORF clone of Human Parkinson disease (autosomal recessive, early onset) 7 (PARK7), transcript variant 1, mGFP tagged • GFP-tagged ORF clone of Homo sapiens Parkinson disease (autosomal recessive, early onset) 7 (PARK7), transcript variant 1 as transfection-ready DNA • Myc-DDK-tagged ORF clone of Homo sapiens Parkinson disease (autosomal recessive, early onset) 7 (PARK7), transcript variant 1 as 200 ug transfection-ready DNA Related Lysate from OriGene • Transient overexpression lysate of Parkinson disease (autosomal recessive, early onset) 7 (PARK7), transcript variant 1 Validated Antibodies • Rabbit Monoclonal Antibody against PARK7 (Clone EP2815Y) • Rabbit Polyclonal Antibody against DJ-1 • Purified Goat Polyclonal Antibody against PARK7 / DJ-1 • Rabbit monoclonal antibody against DJ-1 (clone EP2819Y ) • Rabbit Polyclonal Park7(DJ-1) Antibody • PARK7 / DJ-1 Rabbit Polyclonal (aa177-189) Antibody • Anti-TNNI2 Rabbit Polyclonal Antibody • PARK7 / DJ-1 Rabbit Polyclonal (aa167-189) Antibody Anti-Tag Antibodies & WB Reagent • Anti-Tag Antibodies • Western Blot Reagent shRNA • PARK7 - Human, 4 unique 29mer shRNA constructs in retroviral RFP vector • PARK7 - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector • Park7 - Mouse, 4 unique 29mer shRNA constructs in retroviral GFP vector • PARK7 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector • Park7 - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector Related Primer Pair qSTAR qPCR primer pairs against Homo sapiens gene PARK7

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Protein	Full Length Protein A domain of the protein Description of domain...
Tag	C-fusion N-fusion     Tag Description:
DNA or protein sequence of the final product
Preferred Expression Host	HEK293 E. coli Insect Cells Yeast
The main application with the purified protein	R&D reagent Cell-based Assay Animal Study Other, please specify:
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