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Home Recombinant Human Proteins All BAD Proteins

BAD (NM_004322) Purified Human Protein

Specifications Citations Customer Service Product Documents
Cat. No. Description Datasheet Price Availability*  
TP300634 Recombinant protein of human BCL2-associated agonist of cell death (BAD), transcript variant 1, 20 ug (Larger pack size?) 680
$398
In Stock
TA306174 Rabbit Polyclonal BAD Antibody $325 3-7 Days
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OriGene Data
Species:Human Expression Host:HEK293 cells
Expression cDNA Clone or AA Sequence
Recombinant protein was produced with TrueORF clone, RC200634. Click on the TrueORF clone link to view cDNA and protein sequences.
Tag:C-terminal MYC/DDK Predicted MW:18.2 kDa
Purity:> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration:>50 ug/mL as determined by microplate BCA method
Buffer:25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Protein Families: Druggable Genome
Protein Pathways: ErbB signaling pathwayApoptosisVEGF signaling pathwayFocal adhesionNeurotrophin signaling pathwayInsulin signaling pathwayMore Pathways >>
Protein Data
Protein Image
 

Reference Data
RefSeq: NP_004313 RefSeq Size: 1127 RefSeq ORF: 507
LocusID: 572 Cytogenetic: 11q13.1  
Synonyms : BBC2; BCL2L8
Summary: The protein encoded by this gene is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL and BCL-2, and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein. Alternative splicing of this gene results in two transcript variants which encode the same isoform. [provided by RefSeq, Jul 2008].
*: Inventory for certain proteins may be limited due to low expression level. Delivery time may vary from web posted schedule. Contact techsupport@origene.com for specific inventory information
**: DDK-tag is the same as FLAG tag. Flag® is a registered trademark of Sigma-Aldrich

 

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