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Expression Host: Human HEK293 cells Predicted MW: 54.7 kDa Expression TrueORF clone: RC200524 Protein Sequence: Sequence Link Tag: C-terminal MYC/DDK * Anti-Myc/DDK antibody Protein family: Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining Bioactivity: , view data Concentration: > 50 ug/ml as determined by BCA Endotoxin: < 0.1 EU per 1 μg of the protein by the LAL Buffer and Storage: 10% glycerol, 100 mM glycine, 25 mM Tris-HCl, pH 7.3. Store at -80C. Avoid repeated freeze-thaw cycles. Stable for 3 months from receipt of products under proper storage and handling conditions.

RefSeq: NP_000017 RefSeq Size: 1692 RefSeq ORF: 1455 Synonyms : AMPS; ASASE; ASL LocusID: 158 Cytogenetic: 22q13.2   Summary: Adenylsuccinate lyase is involved in both de novo synthesis of purines and formation of adenosine monophosphate from inosine monophosphate. It catalyzes two reactions in AMP biosynthesis: the removal of a fumarate from succinylaminoimidazole carboxamide (SAICA) ribotide to give aminoimidazole carboxamide ribotide (AICA) and removal of fumarate from adenylosuccinate to give AMP. Adenylosuccinase deficiency results in succinylpurinemic autism, psychomotor retardation, and , in some cases, growth retardation associated with muscle wasting and epilepsy. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].

Researchers who bought this clone have also purchased:

Related ORF Clones • Myc-DDK-tagged ORF clone of Homo sapiens adenylosuccinate lyase (ADSL), transcript variant 1 as transfection-ready DNA • Myc-DDK-tagged ORF clone of Homo sapiens adenylosuccinate lyase (ADSL), transcript variant 2 as transfection-ready DNA • GFP-tagged ORF clone of Homo sapiens adenylosuccinate lyase (ADSL), transcript variant 1 as transfection-ready DNA • GFP-tagged ORF clone of Homo sapiens adenylosuccinate lyase (ADSL), transcript variant 2 as transfection-ready DNA Related Lysate from OriGene • Antigen standard for adenylosuccinate lyase (ADSL), transcript variant 1 (transient overexpression lysate) Anti-Tag Antibodies & WB Reagent • Anti-Tag Antibodies • Western Blot Reagent shRNA • HuSH 29mer shRNA Constructs against ADSL in pRFP-C-RS vector • HuSH 29mer shRNA Constructs against ADSL in pGFP-V-RS vector • shRNA Constructs against Mus musculus Adsl in pGFP-V-RS Vector • HuSH 29mer shRNA Constructs against ADSL • shRNA Constructs against Mus musculus Adsl Related Primer Pair qSTAR qPCR primer pairs against Homo sapiens gene ADSL

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Protein	Full Length Protein A domain of the protein Description of domain...
Tag	N-fusion C-fusion     Tag Description:
DNA or protein sequence of the final product
Preferred Expression Host	HEK293 CHO Other, please specify:
The main application with the purified protein	R&D reagent Cell-based Assay Animal Study Other, please specify:
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