Fluorogenic Cell Assay Kits
Prizm™ Fluorogenic Cell Assay Kits are based on cell-permeable fluorogenic substrates designed to monitor enzymatic activity in biological samples. These substrates diffuse through plasma or intracellular membranes by passive diffusion. Once the substrates are recognized by their corresponding protease, they are cleaved and the fragments produce fluorescence that can help measure the activity of the enzyme. Learn more…
Advantages:
- Live-cell imaging: Enzymatic activity can be measured in tissues, serum and live cells without toxic effects
- In vivo specificity: Fluorescent substrates assume conformations similar to active site loop conformations of naturally occurring target molecules
- Measure multiple proteolytic activities: Variety of fluorophores available
- Convenient: All reagents supplied in kit format, ready for immediate application
- Cost-effective: Flow cytometer for quantitation or fluorometer for detection is sufficient; no modifications needed
Apoptosis Assays Cytotoxicity Assays
Apoptosis Protease Assay (Product Manual)
Prizm™ Fluorogenic Apoptosis Assay Kits are available with green λex=505 nm and Λem=530 nm ) or red (λex=552 nm and λem=580 nm ) fluorescence for the detection and measurement of caspase activities in living cells using flow cytometry or fluorescence microscopy. By combining different substrates in complementary colors, multiple caspase activities can be measured simultaneously in live cells.
| SKU |
Description |
Price |
Ship Date |
Data Sheet |
|
Prizm™ Cell-Mediated Cytotoxicity Assay (Product Manual)
PrizmTM Fluorogenic Cell-Mediated Cytotoxicity Assay are available with green fluorescence for the detection and measurement of Caspase and Granzyme B activities following the successful delivery of a lethal hit by cytotoxic lymphocytes. Enzyme activity can be measured either by flow cytometry or fluorescence microscopy.
| SKU |
Description |
Price |
Ship Date |
Data Sheet |
|
Related Products: