HFE (NM_139004) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC217509L4V

  • LentiORF®

Lenti ORF particles, HFE (mGFP-tagged)-Human hemochromatosis (HFE), transcript variant 4, 200ul, >10^7 TU/mL

ORF Plasmid: DDK tGFP

Lentiviral Particles: DDK w/ Puro mGFP w/ Puro


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USD 880.00

7 Weeks*

Size
    • 200 ul

Product Images

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Specifications

Product Data
Type Human Tagged ORF Clone Lentiviral Particle
Tag mGFP
Symbol HFE
Synonyms HFE1; HH; HLA-H; MVCD7; TFQTL2
Mammalian Cell Selection Puromycin
Vector pLenti-C-mGFP-P2A-Puro
ACCN NM_139004
ORF Size 768 bp
Sequence Data
The ORF insert of this clone is exactly the same as(RC217509).
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Reference Data
RefSeq NM_139004.2
RefSeq Size 1946 bp
RefSeq ORF 771 bp
Locus ID 3077
UniProt ID Q30201
Cytogenetics 6p22.2
Protein Families Druggable Genome, Transmembrane
MW 29.2 kDa
Gene Summary The protein encoded by this gene is a membrane protein that is similar to MHC class I-type proteins and associates with beta2-microglobulin (beta2M). It is thought that this protein functions to regulate iron absorption by regulating the interaction of the transferrin receptor with transferrin. The iron storage disorder, hereditary haemochromatosis, is a recessive genetic disorder that results from defects in this gene. At least nine alternatively spliced variants have been described for this gene. Additional variants have been found but their full-length nature has not been determined. [provided by RefSeq, Jul 2008]

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