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Home cDNA Clone TrueORF All GPX6 ORF Clones

GPX6 (NM_182701) Human cDNA ORF Clone

Specifications Citations Clones of Other Species Product Documents
Cat. No. Description Price Availability  
RC224313 GPX6 (Myc-DDK-tagged)-Human glutathione peroxidase 6 (olfactory) (GPX6), (Note, selenocysteine protein, internal stop codon, see reference data summary), 10µg   
$390
In Stock
RG224313 GPX6 (GFP-tagged) - Human glutathione peroxidase 6 (olfactory) (GPX6), (10ug), (Note: selenocystein protein, Internal stop codon present. See Summary below) $430 In Stock
TA50011-100 4C5, Anti-DDK monoclonal antibody, 100µl $248 In Stock
Cat. No. Description Price Availability
RC524313 0 2 weeks
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Clone Modification
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The same insert cloned in a GFP-tagging vector is also available

Cat. No. Description Vector Price Availability  
RG224313 GPX6 (GFP-tagged) - Human glutathione peroxidase 6 (olfactory) (GPX6), (10ug), (Note: selenocystein protein, Internal stop codon present. See Summary below)

$430 In Stock
TA150041 2H8, Anti-tGFP monoclonal antibody, 100µl Datasheet $248 In Stock
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TrueORF Data for RC224313
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Vector: pCMV6-Entry   Change vector? Tag: C-terminal Myc-DDK
Sequence Data: ORF Nucleotide Sequence
Protein Sequence
ORF Size: 663 bp
Predicted Protein MW: 24.9 kDa
Restriction Sites: SgfI-MluI     Cloning Scheme for this gene     Plasmid Map Plasmid Map
OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
Product Components: The ORF clone is ion-exchange column purified, transfection-ready dried plasmid DNA, and shipped with 2 vector sequencing primers.
Protein Families: Secreted ProteinDruggable Genome
Protein Pathways: Glutathione metabolismArachidonic acid metabolism

Reference Data
RefSeq Explanation: NM_182701.1 , NP_874360
Synonyms: dJ1186N24; dJ1186N24.1; GPx-6; GPX5p; GPXP3; GSHPx-6 RefSeq Size: 1712 RefSeq ORF: 666
LocusID: 257202 Cytogenetic: 6p22.1
Gene Summary: The protein encoded by this gene belongs to the glutathione peroxidase family, members of which catalyze the reduction of hydrogen peroxide, organic hydroperoxides and lipid hydroperoxides, and thereby protect cells against oxidative damage. Several isozymes of this gene family exist in vertebrates, which vary in cellular location and substrate specificity. Expression of this gene has been observed in embryos and olfactory epithelium; however, the exact function of this gene is not known. This isozyme is a selenoprotein in humans, containing the rare amino acid selenocysteine (Sec) at its active site. Sec is encoded by the UGA codon, which normally signals translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, designated the Sec insertion sequence (SECIS) element, that is necessary for the recognition of UGA as a Sec codon, rather than as a stop signal. The orthologs of this gene in mouse and rat (and some other species) contain a cysteine (Cys) residue in place of the Sec residue, and their corresponding mRNAs lack the SECIS elements. [provided by RefSeq, Oct 2016]

 

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