OriGene Logo
Search:    
Left ProductsProducts divider ServicesServices divider technologyTechnology divider researchResearch divider TechsupportTechSupport divider AboutAbout Right
 
Home cDNA Clone TrueORF All GADD45GIP1 ORF Clones
TrueORF Gold

GADD45GIP1 (NM_052850) Human cDNA ORF Clone

Specifications Citations Clones of Other Species Product Documents
Cat. No. Description Price Availability  
RC209644 GADD45GIP1 (Myc-DDK-tagged)-Human growth arrest and DNA-damage-inducible, gamma interacting protein 1 (GADD45GIP1), 10µg   
390
$98
In Stock
RG209644 GADD45GIP1 (GFP-tagged) - Human growth arrest and DNA-damage-inducible, gamma interacting protein 1 (GADD45GIP1) $430 In Stock
TA50011-100 4C5, Anti-DDK monoclonal antibody, 100µl $248 In Stock
Cat. No. Description Price Availability
RC509644 GADD45GIP1 (Myc-DDK-tagged)-Human growth arrest and DNA-damage-inducible, gamma interacting protein 1 (GADD45GIP1), (200ug) $520 2 weeks
Add to Shopping Cart
Clone Modification
spacer

The same insert cloned in a GFP-tagging vector is also available

Cat. No. Description Vector Price Availability  
RG209644 GADD45GIP1 (GFP-tagged) - Human growth arrest and DNA-damage-inducible, gamma interacting protein 1 (GADD45GIP1)

$430 In Stock
TA150041 2H8, Anti-tGFP monoclonal antibody, 100µl Datasheet $248 In Stock
Lenti particle icon Add to Shopping Cart
spacer
Also for GADD45GIP1 (NM_052850)
cDNA Clone shRNA/siRNA CRISPR KO Kit Protein Antibody
TrueORF Data for RC209644
spacer
Vector: pCMV6-Entry   Change vector? Tag: C-terminal Myc-DDK
Western validation with an anti-DDK antibody *
L: Control HEK293 lysate
R: Over-expression lysate
Lysate_Image
Sequence Data: ORF Nucleotide Sequence
Protein Sequence
ORF Size: 666 bp
Predicted Protein MW: 25.2 kDa
Restriction Sites: SgfI-MluI     Cloning Scheme for this gene     Plasmid Map Plasmid Map
OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
Product Components: The ORF clone is ion-exchange column purified, transfection-ready dried plasmid DNA, and shipped with 2 vector sequencing primers.
* The lysates used for this WB picture contain the overexpressed empty vector or the Myc-DDK tagged ORF clone.

Reference Data
RefSeq Explanation: NM_052850.1 NM_052850.2 NM_052850.3 , NP_443082
Synonyms: CKBBP2; CKbetaBP2; CRIF1; MRP-L59; PLINP; PLINP-1; Plinp1; PRG6 RefSeq Size: 744 RefSeq ORF: 669
LocusID: 90480 Cytogenetic: 19p13.13
Gene Summary: Acts as a negative regulator of G1 to S cell cycle phase progression by inhibiting cyclin-dependent kinases. Inhibitory effects are additive with GADD45 proteins but occurs also in the absence of GADD45 proteins. Acts as a repressor of the orphan nuclear receptor NR4A1 by inhibiting AB domain-mediated transcriptional activity. May be involved in the hormone-mediated regulation of NR4A1 transcriptional activity. May play a role in mitochondrial protein synthesis. [UniProtKB/Swiss-Prot Function]

 

spacer
Inc 5000 Healthcare Company

Notice to Non-US Customers

ExclaimationWeb price and delivery time are for direct sales only.

Non-US customers are encouraged to contact our dedicated distributor network for quotes and streamlined ordering/delivery support.

Acknowledge