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Home cDNA Clone TrueORF All MIB1 ORF Clones
TrueORF Gold

MIB1 (NM_020774) Human cDNA ORF Clone

Specifications Citations Clones of Other Species Product Documents
Cat. No. Description Price Availability  
RC221377 MIB1 (Myc-DDK-tagged)-Human mindbomb homolog 1 (Drosophila) (MIB1), 10µg
$1450
In Stock
RC521377 MIB1 (Myc-DDK-tagged)-Human mindbomb homolog 1 (Drosophila) (MIB1), (200ug) $1570 2~3 weeks
TA50011-100 4C5, Anti-DDK monoclonal antibody, 100µl $248 In Stock
Clone Modification

The same insert cloned in Lenti and other vectors is also available.

Cat. No. Description Vector Price Availability  
RC221377L2 Lenti ORF clone of Human mindbomb homolog 1 (Drosophila) (MIB1), mGFP tagged

2000 3 Weeks
TR30022 Lenti-vpak packaging kit - packaging plasmids and transfection reagent (10 rxns) Lenti-vpak-app-guide $390 In Stock
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Also for MIB1 (NM_020774)
cDNA Clone shRNA/siRNA Lysate Protein Antibody
TrueORF Data for RC221377
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Vector: pCMV6-Entry   Change vector? Tag: C-terminal Myc-DDK
Western validation with an anti-DDK antibody *
L: Control HEK293 lysate
R: Over-expression lysate
Lysate_Image
Sequence Data: ORF Nucleotide Sequence
Protein Sequence
ORF Size: 3021 bp
Predicted Protein MW: 110 kDa
Restriction Sites: SgfI-MluI     Cloning Scheme for this gene     Plasmid Map Plasmid Map
OTI Annotation: This clone was engineered to express the complete ORF with an expression tag.
OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
Product Components: The ORF clone is ion-exchange column purified, transfection-ready dried plasmid DNA, and shipped with 2 vector sequencing primers.
Protein Families: Druggable Genome
* The lysates used for this WB picture contain the overexpressed empty vector or the Myc-DDK tagged ORF clone.

Reference Data
RefSeq: NM_020774.2, NP_065825
RefSeq Size: 9308 RefSeq ORF: 3021
Synonyms : DIP-1; DIP1; LVNC7; MIB; ZZANK2; ZZZ6
LocusID: 57534 Cytogenetic: 18q11.2
Summary: This gene encodes a protein containing multiple ankyrin repeats and RING finger domains that functions as an E3 ubiquitin ligase. The encoded protein positively regulates Notch signaling by ubiquitinating the Notch receptors, thereby facilitating their endocytosis. This protein may also promote the ubiquitination and degradation of death-associated protein kinase 1 (DAPK1). [provided by RefSeq, Jun 2013].

 

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