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Home cDNA Clone TrueORF All UGT1A7 ORF Clones

UGT1A7 (NM_019077) Human cDNA ORF Clone

Specifications Citations Clones of Other Species Product Documents
Cat. No. Description Price Availability  
RG216210 UGT1A7 (GFP-tagged) - Human UDP glucuronosyltransferase 1 family, polypeptide A7 (UGT1A7), 10µg
$700
2-3 weeks
TA150041 2H8, Anti-tGFP monoclonal antibody, 100µl $248 In Stock
Clone Modification
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TrueORF Data for RG216210
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Vector: pCMV6-AC-GFP   Change vector? Tag: C-terminal TurboGFP
Sequence Data: ORF Nucleotide Sequence
Protein Sequence
ORF Size: 1593 bp
Restriction Sites: SgfI-MluI     Cloning Scheme for this gene     Plasmid Map Plasmid Map
OTI Annotation: This clone was engineered to express the complete ORF with an expression tag.
OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
Product Components: The ORF clone is ion-exchange column purified, transfection-ready dried plasmid DNA, and shipped with 2 vector sequencing primers.
Protein Families: Transmembrane
Protein Pathways: Pentose and glucuronate interconversionsAscorbate and aldarate metabolismAndrogen and estrogen metabolismStarch and sucrose metabolismRetinol metabolismPorphyrin and chlorophyll metabolismMore Pathways >>

Reference Data
RefSeq: NM_019077.2, NP_061950
RefSeq Size: 2333 RefSeq ORF: 1593
Synonyms : UDPGT; UDPGT 1-7; UGT-1G; UGT1-07; UGT1.7; UGT1G
LocusID: 54577 Cytogenetic: 2q37
Summary: This gene encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter. The enzyme encoded by this gene has moderate glucuronidase activity with phenols. [provided by RefSeq, Jul

 

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