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Home cDNA Clone TrueORF All NRG1 ORF Clones
TrueORF Gold

NRG1 (NM_013961) Human cDNA ORF Clone

Specifications Citations Clones of Other Species Product Documents
Cat. No. Description Price Availability  
RC220302 NRG1 (Myc-DDK-tagged)-Human neuregulin 1 (NRG1), transcript variant GGF, 10µg   
$390
In Stock
RG220302 NRG1 (GFP-tagged) - Human neuregulin 1 (NRG1), transcript variant GGF, (10ug) $430 2-3 weeks
TA50011-100 4C5, Anti-DDK monoclonal antibody, 100µl $248 In Stock
Cat. No. Description Price Availability
RC520302 NRG1 (Myc-DDK-tagged)-Human neuregulin 1 (NRG1), transcript variant GGF, (200ug) $520 4 weeks
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The same insert cloned in a GFP-tagging vector is also available

Cat. No. Description Vector Price Availability  
RG220302 NRG1 (GFP-tagged) - Human neuregulin 1 (NRG1), transcript variant GGF, (10ug)

$430 3 Weeks
TA150041 2H8, Anti-tGFP monoclonal antibody, 100µl Datasheet $248 In Stock
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TrueORF Data for RC220302
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Vector: pCMV6-Entry   Change vector? Tag: C-terminal Myc-DDK
Western validation with an anti-DDK antibody *
L: Control HEK293 lysate
R: Over-expression lysate
Lysate_Image
Sequence Data: ORF Nucleotide Sequence
Protein Sequence
ORF Size: 726 bp
Predicted Protein MW: 26 kDa
Restriction Sites: SgfI-MluI     Cloning Scheme for this gene     Plasmid Map Plasmid Map
OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
Product Components: The ORF clone is ion-exchange column purified, transfection-ready dried plasmid DNA, and shipped with 2 vector sequencing primers.
Protein Families: Secreted ProteinTransmembraneTranscription FactorsDruggable Genome
Protein Pathways: ErbB signaling pathway
* The lysates used for this WB picture contain the overexpressed empty vector or the Myc-DDK tagged ORF clone.

Reference Data
RefSeq Explanation: NM_013961.2, NP_039255 RefSeq Size: 1703 RefSeq ORF: 725
Synonyms : ARIA; GGF; GGF2; HGL; HRG; HRG1; HRGA; NDF; SMDF
LocusID: 3084 Cytogenetic: 8p12 Domains: ig, IGc2, IG, EGF, EGF
Gene Summary: The protein encoded by this gene is a membrane glycoprotein that that mediates cell-cell signaling and plays a critical role in the growth and development of multiple organ systems. An extraordinary variety of different isoforms are produced from this gene through alternative promoter usage and splicing. These isoforms are expressed in a tissue-specific manner and differ significantly in their structure, and are classified as types I, II, III, IV, V and VI. Dysregulation of this gene has been linked to diseases such as cancer, schizophrenia, and bipolar disorder (BPD). [provided by RefSeq, Jun 2014].

 

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