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Home cDNA Clone TrueORF All TGFBR1 ORF Clones
TrueORF Gold

TGFBR1 (NM_004612) Human cDNA ORF Clone

Specifications Citations Clones of Other Species Product Documents
Cat. No. Description Price Availability  
RC219514 TGFBR1 (Myc-DDK-tagged)-Human transforming growth factor, beta receptor 1 (TGFBR1), transcript variant 1, 10µg
$610
In Stock
RC519514 TGFBR1 (Myc-DDK-tagged)-Human transforming growth factor, beta receptor 1 (TGFBR1), transcript variant 1, (200ug) $730 2~3 weeks
TA50011-100 4C5, Anti-DDK monoclonal antibody, 100µl $248 In Stock
Clone Modification

The same insert cloned in Lenti and other vectors is also available.

Cat. No. Description Vector Price Availability  
RC219514L2 Lenti ORF clone of Human transforming growth factor, beta receptor 1 (TGFBR1), transcript variant 1, mGFP tagged

1080 3 Weeks
TR30022 Lenti-vpak packaging kit - packaging plasmids and transfection reagent (10 rxns) Lenti-vpak-app-guide $390 In Stock
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Also for TGFBR1 (NM_004612)
cDNA Clone shRNA/siRNA Lysate Protein Antibody
TrueORF Data for RC219514
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Vector: pCMV6-Entry   Change vector? Tag: C-terminal Myc-DDK
Western validation with an anti-DDK antibody *
L: Control HEK293 lysate
R: Over-expression lysate
Lysate_Image
Sequence Data: ORF Nucleotide Sequence
Protein Sequence
ORF Size: 1512 bp
Predicted Protein MW: 53.6 kDa
Restriction Sites: SgfI-MluI     Cloning Scheme for this gene     Plasmid Map Plasmid Map
OTI Annotation: This clone was engineered to express the complete ORF with an expression tag.
OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
Product Components: The ORF clone is ion-exchange column purified, transfection-ready dried plasmid DNA, and shipped with 2 vector sequencing primers.
Protein Families: Protein KinaseTransmembraneDruggable Genome
Protein Pathways: MAPK signaling pathwayCytokine-cytokine receptor interactionEndocytosisTGF-beta signaling pathwayAdherens junctionPathways in cancerMore Pathways >>
* The lysates used for this WB picture contain the overexpressed empty vector or the Myc-DDK tagged ORF clone.

Reference Data
RefSeq: NM_004612.2, NP_004603
RefSeq Size: 6475 RefSeq ORF: 1512
Synonyms : AAT5; ACVRLK4; ALK-5; ALK5; ESS1; LDS1; LDS1A; LDS2A; MSSE; SKR4; TGFR-1
LocusID: 7046 Cytogenetic: 9q22 Domains: Activin_recp, pkinase, TyrKc, S_TKc, GS
Summary: The protein encoded by this gene forms a heteromeric complex with type II TGF-beta receptors when bound to TGF-beta, transducing the TGF-beta signal from the cell surface to the cytoplasm. The encoded protein is a serine/threonine protein kinase. Mutations in this gene have been associated with Loeys-Dietz aortic aneurysm syndrome (LDAS). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008].

 

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