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Home cDNA Clone TrueORF All TNFRSF10D ORF Clones
TrueORF Gold

TNFRSF10D (NM_003840) Human cDNA ORF Clone

Specifications Citations Clones of Other Species Product Documents
Cat. No. Description Price Availability  
RC208547 TNFRSF10D (Myc-DDK-tagged)-Human tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain (TNFRSF10D), 10µg   
$560
In Stock
RG208547 TNFRSF10D (GFP-tagged) - Human tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain (TNFRSF10D) $610 In Stock
TA50011-100 4C5, Anti-DDK monoclonal antibody, 100µl $248 In Stock
Cat. No. Description Price Availability
RC508547 0 2 weeks
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Clone Modification
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The same insert cloned in a GFP-tagging vector is also available

Cat. No. Description Vector Price Availability  
RG208547 TNFRSF10D (GFP-tagged) - Human tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain (TNFRSF10D)

$610 In Stock
TA150041 2H8, Anti-tGFP monoclonal antibody, 100µl Datasheet $248 In Stock
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TrueORF Data for RC208547
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Vector: pCMV6-Entry   Change vector? Tag: C-terminal Myc-DDK
Western validation with an anti-DDK antibody *
L: Control HEK293 lysate
R: Over-expression lysate
Lysate_Image
Sequence Data: ORF Nucleotide Sequence
Protein Sequence
ORF Size: 1158 bp
Predicted Protein MW: 41.7 kDa
Restriction Sites: SgfI-MluI     Cloning Scheme for this gene     Plasmid Map Plasmid Map
OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
Product Components: The ORF clone is ion-exchange column purified, transfection-ready dried plasmid DNA, and shipped with 2 vector sequencing primers.
Protein Families: TransmembraneDruggable Genome
Protein Pathways: Cytokine-cytokine receptor interactionApoptosisNatural killer cell mediated cytotoxicity
* The lysates used for this WB picture contain the overexpressed empty vector or the Myc-DDK tagged ORF clone.

Reference Data
RefSeq Explanation: NM_003840.1 NM_003840.2 NM_003840.3 NM_003840.4 , NP_003831
Synonyms: CD264; DCR2; TRAIL-R4; TRAILR4; TRUNDD RefSeq Size: 3561 RefSeq ORF: 1161
LocusID: 8793 Cytogenetic: 8p21.3 Domains: TNFR
Gene Summary: Receptor for the cytotoxic ligand TRAIL. Contains a truncated death domain and hence is not capable of inducing apoptosis but protects against TRAIL-mediated apoptosis. Reports are contradictory with regards to its ability to induce the NF-kappa-B pathway. According to PubMed:9382840, it cannot but according to PubMed:9430226, it can induce the NF-kappa-B pathway. [UniProtKB/Swiss-Prot Function]

 

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