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Home cDNA Clone TrueORF All APH1B ORF Clones

APH1B (NM_001145646) Human cDNA ORF Clone

Specifications Citations Clones of Other Species Product Documents
Cat. No. Description Price Availability  
RC226500 APH1B (Myc-DDK-tagged)-Human anterior pharynx defective 1 homolog B (C. elegans) (APH1B), transcript variant 2, 10µg   
$390
In Stock
RG226500 APH1B (GFP-tagged) - Human anterior pharynx defective 1 homolog B (C. elegans) (APH1B), transcript variant 2, (10ug) $430 2-3 weeks
TA50011-100 4C5, Anti-DDK monoclonal antibody, 100µl $248 In Stock
Cat. No. Description Price Availability
RC526500 0 4 weeks
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Clone Modification
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The same insert cloned in a GFP-tagging vector is also available

Cat. No. Description Vector Price Availability  
RG226500 APH1B (GFP-tagged) - Human anterior pharynx defective 1 homolog B (C. elegans) (APH1B), transcript variant 2, (10ug)

$430 3 Weeks
TA150041 2H8, Anti-tGFP monoclonal antibody, 100µl Datasheet $248 In Stock
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TrueORF Data for RC226500
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Vector: pCMV6-Entry   Change vector? Tag: C-terminal Myc-DDK
Sequence Data: ORF Nucleotide Sequence
Protein Sequence
ORF Size: 651 bp
Predicted Protein MW: 24.1 kDa
Restriction Sites: SgfI-MluI     Cloning Scheme for this gene     Plasmid Map Plasmid Map
OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
Product Components: The ORF clone is ion-exchange column purified, transfection-ready dried plasmid DNA, and shipped with 2 vector sequencing primers.
Protein Families: Transmembrane

Reference Data
RefSeq Explanation: NM_001145646.1, NP_001139118 RefSeq Size: RefSeq ORF: 651
Synonyms : APH-1B; PRO1328; PSFL; TAAV688
LocusID: 83464 Cytogenetic: 15q22.2
Gene Summary: This gene encodes a multi-pass transmembrane protein that is a functional component of the gamma-secretase complex, which also contains presenilin and nicastrin. This protein represents a stabilizing cofactor for the presenilin holoprotein in the complex. The gamma-secretase complex catalyzes the cleavage of integral proteins such as notch receptors and beta-amyloid precursor protein. [provided by RefSeq, Sep 2011].

 

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