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Home cDNA Clone TrueORF All PLAU ORF Clones

PLAU (NM_001145031) Human cDNA ORF Clone

Specifications Citations Clones of Other Species Product Documents
Cat. No. Description Price Availability  
RC227661 PLAU (Myc-DDK-tagged)-Human plasminogen activator, urokinase (PLAU), transcript variant 2, 10µg   
$520
In Stock
RG227661 PLAU (GFP-tagged) - Human plasminogen activator, urokinase (PLAU), transcript variant 2, (10ug) $570 2-3 weeks
TA50011-100 4C5, Anti-DDK monoclonal antibody, 100µl $248 In Stock
Cat. No. Description Price Availability
RC527661 0 4 weeks
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Clone Modification
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The same insert cloned in Lenti and other vectors are also available.

Cat. No. Description Vector Price Availability  
RC227661L1 Lenti-ORF clone of PLAU (Myc-DDK-tagged)-Human plasminogen activator, urokinase (PLAU), transcript variant 2, (10ug)

$700 4 Weeks
TR30022 Lenti-vpak packaging kit - packaging plasmids and transfection reagent (10 rxns) Lenti-vpak-app-guide $390 In Stock
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TrueORF Data for RC227661
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Vector: pCMV6-Entry   Change vector? Tag: C-terminal Myc-DDK
Sequence Data: ORF Nucleotide Sequence
Protein Sequence
ORF Size: 1245 bp
Predicted Protein MW: 46.7 kDa
Restriction Sites: SgfI-MluI     Cloning Scheme for this gene     Plasmid Map Plasmid Map
OTI Annotation: This clone was engineered to express the complete ORF with an expression tag.
OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
Product Components: The ORF clone is ion-exchange column purified, transfection-ready dried plasmid DNA, and shipped with 2 vector sequencing primers.
Protein Families: ES Cell Differentiation/IPSProteaseDruggable Genome
Protein Pathways: Complement and coagulation cascades

Reference Data
RefSeq Explanation: NM_001145031.1, NP_001138503 RefSeq Size: RefSeq ORF: 1245
Synonyms : ATF; BDPLT5; QPD; u-PA; UPA; URK
LocusID: 5328 Cytogenetic: 10q22.2
Gene Summary: This gene encodes a secreted serine protease that converts plasminogen to plasmin. The encoded preproprotein is proteolytically processed to generate A and B polypeptide chains. These chains associate via a single disulfide bond to form the catalytically inactive high molecular weight urokinase-type plasminogen activator (HMW-uPA). HMW-uPA can be further processed into the catalytically active low molecular weight urokinase-type plasminogen activator (LMW-uPA). This low molecular weight form does not bind to the urokinase-type plasminogen activator receptor. Mutations in this gene may be associated with Quebec platelet disorder and late-onset Alzheimer's disease. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Jan 2016].

 

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