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Home cDNA Clone TrueORF All BEST1 ORF Clones

BEST1 (NM_001139443) Human cDNA ORF Clone

Specifications Citations Clones of Other Species Product Documents
Cat. No. Description Price Availability  
RC227442 BEST1 (Myc-DDK-tagged)-Human bestrophin 1 (BEST1), transcript variant 2, 10µg   
In Stock
RG227442 BEST1 (GFP-tagged) - Human bestrophin 1 (BEST1), transcript variant 2, (10ug) $610 2-3 weeks
TA50011-100 4C5, Anti-DDK monoclonal antibody, 100µl $248 In Stock
Cat. No. Description Price Availability
RC527442 0 4 weeks
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Clone Modification

The same insert cloned in Lenti and other vectors are also available.

Cat. No. Description Vector Price Availability  
RC227442L1 Lenti ORF clone of Human bestrophin 1 (BEST1), transcript variant 2 , Myc-DDK-tagged

$740 In Stock
TR30022 Lenti-vpak packaging kit - packaging plasmids and transfection reagent (10 rxns) Lenti-vpak-app-guide $390 In Stock
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TrueORF Data for RC227442
Vector: pCMV6-Entry   Change vector? Tag: C-terminal Myc-DDK
Sequence Data: ORF Nucleotide Sequence
Protein Sequence
ORF Size: 1815 bp
Predicted Protein MW: 68.9 kDa
Restriction Sites: SgfI-MluI     Cloning Scheme for this gene     Plasmid Map Plasmid Map
OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
Product Components: The ORF clone is ion-exchange column purified, transfection-ready dried plasmid DNA, and shipped with 2 vector sequencing primers.
Protein Families: Ion Channels: OtherTransmembraneDruggable Genome

Reference Data
RefSeq Explanation: NM_001139443.1, NP_001132915 RefSeq Size: RefSeq ORF: 1815
Synonyms : ARB; BEST; BMD; RP50; TU15B; VMD2
LocusID: 7439 Cytogenetic: 11q13
Gene Summary: This gene encodes a member of the bestrophin gene family. This small gene family is characterized by proteins with a highly conserved N-terminus with four to six transmembrane domains. Bestrophins may form chloride ion channels or may regulate voltage-gated L-type calcium-ion channels. Bestrophins are generally believed to form calcium-activated chloride-ion channels in epithelial cells but they have also been shown to be highly permeable to bicarbonate ion transport in retinal tissue. Mutations in this gene are responsible for juvenile-onset vitelliform macular dystrophy (VMD2), also known as Best macular dystrophy, in addition to adult-onset vitelliform macular dystrophy (AVMD) and other retinopathies. Alternative splicing results in multiple variants encoding distinct isoforms.[provided by RefSeq, Nov 2008].


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